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Identification of Novel BACE1 Inhibitors by Combination of Pharmacophore Modeling, Structure-Based Design and In Vitro Assay

Journal: Current Computer-Aided Drug Design
Volume: 12 Issue: 1 Year: 2016 Page: 73-82
Author(s): Yuan Ju,Zicheng Li,Yong Deng,Aiping Tong,Liangxue Zhou,Youfu Luo

Discrimination of Active and Weakly Active Human BACE1 Inhibitors Using Self-Organizing Map and Support Vector Machine

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 19 Issue: 6 Year: 2016 Page: 470-480
Author(s): Hang Li,Maolin Wang,Ya-Nan Gong,Aixia Yan

Neuroprotective Activities of Marine Natural Products from Marine Sponges

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 4 Year: 2016 Page: 360-382
Author(s): Mousa Alghazwi,Yen Qi Kan,Wei Zhang,Wei Ping Gai,Xiao-Xin Yan

Designing Multi-Targeted Therapeutics for the Treatment of Alzheimer's Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 17 Year: 2016 Page: 1889-1896
Author(s): Ilkay Erdogan Orhan,F. Sezer Senol

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2016 Page: 1135-1153
Author(s): Catherine F. Latham, Jennifer La, Ricky N. Tinetti, David K. Chalmers, Gilda Tachedjian

Targeting Insulin Signaling for the Treatment of Alzheimer's Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 5 Year: 2016 Page: 485-492
Author(s): Yanxing Chen,Jianfang Zhang,Baorong Zhang,Cheng-Xin Gong

Heterocyclic Scaffolds for the Treatment of Alzheimer’s Disease

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 26 Year: 2016 Page: 3971-3995
Author(s): Annamaria Martorana,Valentina Giacalone,Riccardo Bonsignore,Andrea Pace,Carla Gentile,Ivana Pibiri,Silvestre Buscemi,Antonino Lauria,Antonio Palumbo Piccionello

Advances in Computational Structure-Based Drug Design and Application in Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 9 Year: 2016 Page: 901-916
Author(s): Tao Wang,Mian-Bin Wu,Ri-Hao Zhang,Zheng-Jie Chen,Chen Hua,Jian-Ping Lin,Li-Rong Yang

Anti-Alzheimer Therapeutic Drugs Targeting γ-Secretase

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 5 Year: 2016 Page: 549-557
Author(s): Yan Tan,Qi Zhang,Steven G. Wong,Qian Hua

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15 Issue: 8 Year: 2016 Page: 935-944
Author(s): Ki Young Shin, Su-Jin Noh, Cheol Hyoung Park, Yun Ha Jeong, Keun-A Chang, Jakyung Yoo, Hee Jin Kim, Sungji Ha, Hye-Sun Kim, Hyun-Ju Park, Jun-Ho Lee, Cheil Moon, Yoo-Hun Suh