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Difference in Desipramine Metabolic Profile Between Wild-Type and CYP2D6-Humanized Mice

Journal: Drug Metabolism Letters
Volume: 3 Issue: 4 Year: 2009 Page: 234-241
Author(s): Hong-Wu Shen, Ai-Ming Yu

Medicinal Chemistry Strategies to Reduce CYP2D6 Inhibitory Activity of Lead Candidates

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2009 Page: 3093-3121
Author(s): Bertrand Le Bourdonnec, Lara K. Leister

Metabolism of Loratadine and Further Characterization of Its In Vitro Metabolites

Journal: Drug Metabolism Letters
Volume: 3 Issue: 3 Year: 2009 Page: 162-170
Author(s): Anima Ghosal, Samir Gupta, Ragu Ramanathan, Yuan Yuan, Xiaowen Lu, Ai Duen (Iris) Su, Narciso Alvarez, Shmuel Zbaida, Swapan K. Chowdhury, Kevin B. Alton

Substrate Specificity, Inhibitors and Regulation of Human Cytochrome P450 2D6 and Implications in Drug Development

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2009 Page: 2661-2805
Author(s): Shu-Feng Zhou, Jun-Ping Liu, Xin-Sheng Lai

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 8 Issue: 2 Year: 2009 Page: 164-168
Author(s): Thorsten Nolting, Gabriele Arendt

Inhibitory Properties of Trapping Agents: Glutathione, Potassium Cyanide, and Methoxylamine, Against Major Human Cytochrome P450 Isoforms

Journal: Drug Metabolism Letters
Volume: 3 Issue: 2 Year: 2009 Page: 125-129
Author(s): Chenghong Zhang, Susan Wong, Erlie M. Delarosa, Jane R. Kenny, Jason S. Halladay, Cornelis E. Hop, Siamak Cyrus Khojasteh-Bakht

The Design and Development of Fesoterodine as a Prodrug of 5- Hydroxymethyl Tolterodine (5-HMT), the Active Metabolite of Tolterodine

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 3 Year: 2009 Page: 4481-4489
Author(s): B. Malhotra, K. Gandelman, R. Sachse, N. Wood, M. C. Michel

Pharmacogenomics in Drug Induced Liver Injury

Journal: Current Drug Metabolism
Volume: 10 Issue: 9 Year: 2009 Page: 956-970
Author(s): Raul J. Andrade, Jose A.G. Agundez, M. Isabel Lucena, Carmen Martinez, Raquel Cueto, Elena Garcia-Martin

Oxidation of Endobiotics Mediated by Xenobiotic-Metabolizing Forms of Human Cytochrome P450

Journal: Current Drug Metabolism
Volume: 10 Issue: 7 Year: 2009 Page: 700-712
Author(s): Toshiro Niwa, Norie Murayama, Hiroshi Yamazaki

Transcriptional Regulation of Cytochrome P450 Genes by the Nuclear Receptor Hepatocyte Nuclear Factor 4-Alpha

Journal: Current Drug Metabolism
Volume: 10 Issue: 5 Year: 2009 Page: 508-519
Author(s): Ramiro Jover, Marta Moya, M. Jose Gomez-Lechon