Search Result "Imatinib"


General Research Article

A Validated 2D-LC-UV Method for Simultaneous Determination of Imatinib and N-desmethylimatinib in Plasma and Its Clinical Application for Therapeutic Drug Monitoring with GIST Patients

Journal: Current Pharmaceutical Analysis
Volume: 17 Issue: 0 Year: 2021 Page: 1-10
Author(s): Houli Li,Di Zhang,Xiaoliang Cheng,Qiaowei Zheng,Kai Cheng,Lilong Xiong,Maoyi Wang,Weihua Dong,Weiyi Feng

Research Article

In vitro Measurement and In vivo Prediction of Time-Dependent Inhibitory Effects of Three Tyrosine Kinase Inhibitors on CYP3A Activity

Journal: Current Drug Metabolism
Volume: 22 Issue: 1 Year: 2021 Page: 802-810
Author(s): Liyan Wang,Tingting Zhao,Yunxiang Wang,Banglian Hu,Jianfei Tao,Jinshan Ke,Tingfei Wei,Guangbo Ge,Qiang Meng,Changyuan Wang,Qi Liu,Huijun Sun,Jingjing Wu,Yanwei Chen

Research Article

A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 9 Year: 2021 Page: 1099-1109
Author(s): Ebru Zeytün,Mehlika D. Altıntop,Belgin Sever,Ahmet Özdemir,Doha E. Ellakwa,Zeynep Ocak,Halil I. Ciftci,Masami Otsuka,Mikako Fujita,Mohamed O. Radwan

Research Article

Synthesis of Some Novel Benzimidazole Derivatives as Anticancer Agent, and Evaluation for CDK2 Inhibition Activity

Journal: Medicinal Chemistry
Volume: 17 Issue: 0 Year: 2021 Page: 1-11
Author(s): Rania Helmy Abd El-Hameed,Samar Said Fatahala,Amira Ibrahim Sayed

Research Article

In silico Docking Studies of Vascular Endothelial Growth Factor-A (VEGFA): Possible Implications in Chronic Myeloid Leukemia (CML) Therapy

Journal: Current Proteomics
Volume: 18 Issue: 4 Year: 2021 Page: 575-586
Author(s): Samyuktha Lakkireddy,Archana Jayaraman,Sangeetha Aula,Atya Kapley,Vijay Kumar Kutala,Kaiser Jamil

Research Article

Effect of Dasatinib on Genes Related to Mitotic Catastrophe Pathway in Chronic Myeloid Leukemia Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 1 Year: 2021 Page: 1724-1731
Author(s): Sezgi Kipcak,Buket Ozel,Cigir Biray Avci,Leila S. Takanlou,Maryam S. Takanlou,Cumhur Gunduz,Nur Selvi Gunel

Research Article

Multi-objective Genetic Algorithm for De Novo Drug Design (MoGADdrug)

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 3 Year: 2021 Page: 445-457
Author(s): R. Vasundhara Devi,S. Siva Sathya,Mohane S. Coumar

Research Article

Synthesis, Cytotoxicity Evaluation and Molecular Docking of Fluorine Containing Hexahydroquinoline-3-Carbonitrile Derivatives

Journal: Current Drug Discovery Technologies
Volume: 18 Issue: 0 Year: 2021 Page: 1-11
Author(s): Nishith Teraiya,Subhas Karki,Ashlesha Chauhan

Review Article

Repurposing of Acriflavine to Target Chronic Myeloid Leukemia Treatment

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 1 Year: 2021 Page: 2218-2233
Author(s): Rawan Nehme,Rawan Hallal,Maya El Dor,Firas Kobeissy,Fabrice Gouilleux,Frédéric Mazurier,Kazem Zibara

Research Article

Effective Downregulation of BCR-ABL Tumorigenicity by RNA Targeted CRISPR-Cas13a

Journal: Current Gene Therapy
Volume: 21 Issue: 3 Year: 2021 Page: 270-277
Author(s): Aditya Singh,Prateek Bhatia

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