Search Result "Mutants"


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Temporal Expression of Mutant TDP-43 Correlates with Early Amyotrophic Lateral Sclerosis Phenotype and Motor Weakness

Journal: Current Neurovascular Research
Volume: 15 Issue: 1 Year: 2018 Page: 3-9
Author(s): Qihua Chen,Jinxia Zhou,Cao Huang,Bo Huang,Fangfang Bi,Hongxia Zhou,Bo Xiao

Review Article

Back to the Bench? MEK and ERK Inhibitors for the Treatment of KRAS Mutant Lung Adenocarcinoma

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 5 Year: 2018 Page: 558-574
Author(s): Jens Kohler,Marco Catalano,Chiara Ambrogio

Research Article

3D-QSAR Studies on New Benzothiazole-Based Dual Functional Inhibitors of BCR-ABL Kinase Including the T315I Mutant

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 1 Year: 2018 Page: 1046-1056
Author(s): Shunlai Li,Chaorui Ren,Chenghu Lu,Xiuxiu Li,Hongguang Du

Research Article

Comparative Molecular Characterization to Reveal Surface Behaviour of Non-proteolytic Bromelain Mutants

Journal: Current Pharmaceutical Biotechnology
Volume: 19 Issue: 1 Year: 2018 Page: 886-895
Author(s): Soundhara G Rajan,Ankita Sharma,Pooja Kumari,Sagarika Biswas

Research Article

Improving Xylose Utilization of Saccharomyces cerevisiae by Expressing the MIG1 Mutant from the Self-Flocculating Yeast SPSC01

Journal: Protein & Peptide Letters
Volume: 25 Issue: 2 Year: 2018 Page: 202-207
Author(s): Jian-Ren Xu,Xin-Qing Zhao,Chen-Guang Liu,Feng-Wu Bai

Research Article

Transglycosylation Activity of Catalytic Domain Mutant of Endo-1,3-β-glucanase from Cellulosimicrobium cellulans

Journal: Protein & Peptide Letters
Volume: 25 Issue: 8 Year: 2018 Page: 734-739
Author(s): Yoshiji Hantani,Shoko Motoki,Atsushi Miyagawa,Hatsuo Yamamura,Masayuki Oda

Research Article

Tandem Mass Spectrometric Cell Wall Proteome Profiling of a Candida albicans hwp2 Mutant Strain

Journal: Current Molecular Pharmacology
Volume: 11 Issue: 3 Year: 2018 Page: 211-225
Author(s): Andy Awad,Pamela El Khoury,Brigitte Wex,Roy A. Khalaf

Research Article

Conformational Changes Induced by P32T Substitution in Human Phosphatase ITPA

Journal: Current Chemical Biology
Volume: 12 Issue: 2 Year: 2018 Page: 158-168
Author(s): Ermuhammad B. Dushanov,Natalia A. Koltovaya

Review Article

Development of Novel Therapeutics Targeting Isocitrate Dehydrogenase Mutations in Cancer

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 6 Year: 2018 Page: 505-524
Author(s): Horrick Sharma

Review Article

Enasidenib: First Mutant IDH2 Inhibitor for the Treatment of Refractory and Relapsed Acute Myeloid Leukemia

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1936-1951
Author(s): Raghav Dogra,Rohit Bhatia,Ravi Shankar,Parveen Bansal,Ravindra K. Rawal

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