Search Result "Mutants"


Review Article

Targeting Mutant KRAS for Anticancer Therapy

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2098-2113
Author(s): Fengqian Chen,Martin P. Alphonse,Yan Liu,Qi Liu

Review Article

Small Molecules Targeting Mutant P53: A Promising Approach for Cancer Treatment

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 4 Year: 2019 Page: 7323-7336
Author(s): Elizabeth A. Lopes,Sara Gomes,Lucília Saraiva,Maria M.M. Santos

Research Article

Identification of New Inhibitors of Mutant Isocitrate Dehydrogenase 2 through Molecular Similarity-based Virtual Screening

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 8 Year: 2019 Page: 861-867
Author(s): Lijun Yang,Stefan Pusch,Victoria Jennings,Tianfang Ma,Qihua Zhu,Yungen Xu,Andreas von Deimling,Xiaoming Zha

Editorial free to download

Drug Discovery by Targeting Mutant KRAS

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2079-2080
Author(s): Na Ye

Research Article

Expression and Solution NMR Study of Multi-site Phosphomimetic Mutant BCL-2 Protein

Journal: Protein & Peptide Letters
Volume: 26 Issue: 6 Year: 2019 Page: 449-457
Author(s): Ting Song,Keke Cao,Yu dan Fan,Zhichao Zhang,Zong W. Guo,Min H. Zhang,Peng Liu

Research Article

Anti-viral Effects of Superpositively Charged Mutant of Green Fluorescent Protein

Journal: Protein & Peptide Letters
Volume: 26 Issue: 1 Year: 2019 Page: 930-939
Author(s): Rouhollah Vahabpour,Parya Basimi,Farzin Roohvand,Hassan Asadi,Gholnaz Ms. Irani,Rezvan Zabihollahi,Azam Bolhassani

Research Article

Effect of Substitution Pro32Thr on the Interaction between Dimer Subunits of Human Phosphatase ITPA

Journal: Current Enzyme Inhibition
Volume: 15 Issue: 1 Year: 2019 Page: 45-53
Author(s): Ermuhammad B. Dushanov,Natalia A. Koltovaya

Review Article

KRAS: A Promising Therapeutic Target for Cancer Treatment

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2081-2097
Author(s): Hai-Zhou Wu,Jia-Qi Xiao,Song-Shu Xiao,Yan Cheng

Research Article

Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7- ones Derivatives as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 8 Year: 2019 Page: 826-834
Author(s): Ao Niu,Yang Wang,Yushe Yang,Jianhai Wei,Jian Ding,Yi Chen,Linjiang Tong,Hua Xie

Letter Article

FoxF1 is Required for Ciliogenesis and Distribution of Sonic Hedgehog Signaling Components in Cilium

Journal: Current Molecular Medicine
Volume: 19 Issue: 5 Year: 2019 Page: 326-334
Author(s): Lu Huang,Marco Tjakra,Desha Luo,Lin Wen,Daoxi Lei,Jinxuan Wang,Tieying Yin,Xiaojuan Zhang,Junli Huang,Yeqi Wang,Guixue Wang

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