Search Result "P-glycoprotein efflux transport"


P-Glycoprotein, but not Multidrug Resistance Protein 4, Plays a Role in the Systemic Clearance of Irinotecan and SN-38 in Mice

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 195-201
Author(s): Michael Tagen, Yanli Zhuang, Fan Zhang, K. Elaine Harstead, Jun Shen, Paula Schaiquevich, Charles H. Fraga, John C. Panetta, Christopher M. Waters, Clinton F. Stewart

Transporters in the Brain Endothelial Barrier

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2010 Page: 1125-1138
Author(s): M. Ueno, T. Nakagawa, B. Wu, M. Onodera, C.-l. Huang, T. Kusaka, N. Araki, H. Sakamoto

P-Glycoprotein Is Not a Key Target for the Chemosensitizing Effect of 1-Phenyl-2-Decanoylamino-3-Morpholino-1-Propanol in HepG2 Cells Exposed to Doxorubicin

Journal: Drug Metabolism Letters
Volume: 4 Issue: 1 Year: 2010 Page: 39-44
Author(s): Sabrina Di Bartolomeo, Paolo Luly, Angelo Spinedi

Structural Contributions of Substrates to their Binding to P-Glycoprotein. A TOPSMODE Approach

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 2676-2709
Author(s): Ernesto Estrada, Enrique Molina, Delvin Nodarse, Eugenio Uriarte

Membrane Drug Transport in Helminths

Journal: Anti-Infective Agents in Medicinal Chemistry
Volume: 9 Issue: 3 Year: 2010 Page: 113-129
Author(s): Dominique Kerboeuf, Mickael Riou, Cedric Neveu, Mohamed Issouf

Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 9 Year: 2010 Page: 716-729
Author(s): A. S. Darwich, S. Neuhoff, M. Jamei, A. Rostami-Hodjegan

Substrates, Inhibitors and Activators of P-glycoprotein: Candidates for Radiolabeling and Imaging Perspectives

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1703-1714
Author(s): Nicola A. Colabufo, Francesco Berardi, Maria Grazia Perrone, Elena Capparelli, Mariangela Cantore, Carmela Inglese, Roberto Perrone

Using PET Studies of P-gp Function to Elucidate Mechanisms Underlying the Disposition of Drugs

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1799-1809
Author(s): Stina Syvanen, Margareta Hammarlund-Udenaes

High-Density Lipoprotein: Key Molecule in Cholesterol Efflux and the Prevention of Atherosclerosis

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 1 Year: 2010 Page: 1445-1467
Author(s): Illiana Meurs, Miranda Van Eck, Theo J.C. Van Berkel

PET Imaging of MRP1 Function in the Living Brain: Method Development and Future Perspectives

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 1810-1819
Author(s): T. Okamura, T. Kikuchi, T. Irie

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