Search Result "bioisosterism"


Isosteric and Spatial Considerations of Drugs

Ebook: The Art and Science of Poisons

Volume: 1 Year: 2018
Author(s): M. O. Faruk Khan,Timothy J. Hubin
Doi: 10.2174/97816810868731180101
Research Article

Antihelminthic Activity of Some 2-Substituted Thieno[2,3-d]pyrimidin-4-ones

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 8 Year: 2018 Page: 887-894
Author(s): Anelia Mavrova,Stefan Dimov,Dimitar Vuchev,Kameliya Anichina,Denitsa Yancheva

Review Article

A Review of 2,3-Benzodiazepine-related Compounds: Diazepines and 1,2,5- Triazepines Fused with Five-membered Nitrogen Heterocycles

Journal: Current Organic Synthesis
Volume: 15 Issue: 6 Year: 2018 Page: 729-754
Author(s): Tamas Foldesi,Balazs Volk,Matyas Milen

Review Article

Advances in the Development of Novel Factor Xa Inhibitors: A Patent Review

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1332-1353
Author(s): Atul N Khadse,Mayank Kumar Sharma,Prashant R Murumkar,Sadhana J Rajput,Mange Ram Yadav

Research Article

Synthesis and Antioxidant Activities of Ferrocenyl-containing Curcumin Analogues

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 1 Year: 2018 Page: 1252-1258
Author(s): Xianjiao Meng,Shengling Li,Wenbing Ma,Jianlong Wang,Zhiyong Hu,Duanlin Cao

Research Article

Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 8 Year: 2018 Page: 1184-1196
Author(s): Abdel-Ghany A El-Helby,Rezk R. A. Ayyad,Helmy Sakr,Khaled El-Adl,Mamdouh M Ali,Fathalla Khedr

Review Article

Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC)-Mediated Macrocyclization of Peptides: Impact on Conformation and Biological Activity

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 7 Year: 2018 Page: 591-610
Author(s): Chiara Testa,Anna Maria Papini,Michael Chorev,Paolo Rovero

Review Article

Recent Developments on Phenstatins as Potent Antimitotic Agents

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 2 Year: 2018 Page: 2329-2352
Author(s): Xing Chen,Shi-Meng Wang,Gajjela Bharath Kumar,Grant A.L. Bare,Jing Leng,Syed Nasir Abbas Bukhari,Hua-Li Qin

Review Article

The Renal Outer Medullary Potassium Channel (ROMK): An Intriguing Pharmacological Target for an Innovative Class of Diuretic Drugs

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 2 Year: 2018 Page: 2627-2636
Author(s): Vincenzo Calderone,Alma Martelli,Eugenia Piragine,Valentina Citi,Lara Testai,Maria C. Breschi

Review Article

Quinoxalinone as a Privileged Platform in Drug Development

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2018 Page: 392-413
Author(s): Leilei Shi,Wei Hu,Jifeng Wu,Huaiyu Zhou,Hua Zhou,Xun Li

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