Search Result "bioisosterism"


Use of Bioisosteric Functional Group Replacements or Modifications for Improved Environmental Health

Ebook: Turbulent Flow and Boundary Layer Theory: Selected Topics and Solved Problems

Volume: 1 Year: 2021
Author(s): Jaya Pandey,Nidhi Singh
Doi: 10.2174/97898149983071210101
Research Article

Computational Bioactivity Analysis and Bioisosteric Investigation of the Approved Breast Cancer Drugs Proposed New Design Drug Compounds: Increased Bioactivity Coming with Silicon and Boron

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 6 Year: 2021 Page: 551-561
Author(s): Esma Eryilmaz Dogan

Research Article

Voltage-Dependent Sodium Channel Blocker Anticonvulsants: An Approach to the Structure-Activity Relationship

Journal: Medicinal Chemistry
Volume: 17 Issue: 9 Year: 2021 Page: 1023-1045
Author(s): M. del Carmen Salazar-López,J. Alberto Guevara-Salazar,Mónica G. Arellano-Mendoza,Hugo A. Jiménez-Vázquez,Adriana Benavides,Delia Quintana-Zavala

Mini-Review Article

Advance Synthetic Approaches to 1,2,3-triazole Derived Compounds: State of the Art 2004-2020

Journal: Current Organocatalysis
Volume: 8 Issue: 0 Year: 2021 Page: 1-18
Author(s): Adarsh Sahu

General Review Article

Fused and Substituted Pyrimidine Derivatives as Profound Anti-cancer Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 7 Year: 2021 Page: 861-893
Author(s): Nahid Abbas,Gurubasavaraja S.P. Matada,Prasad S. Dhiwar,Shilpa Patel,Giles Devasahayam

Review Article

Synthesis and Anticancer Properties of ‘azole’ based Chemotherapeutics as Emerging Chemical Moieties: A Comprehensive Review

Journal: Current Organic Chemistry
Volume: 25 Issue: 6 Year: 2021 Page: 654-668
Author(s): Parteek Prasher,Mousmee Sharma,Flavia Zacconi,Gaurav Gupta,Alaa A.A. Aljabali,Vijay Mishra,Murtaza M. Tambuwala,Deepak N. Kapoor,Poonam Negi,Terezinha de Jesus Andreoli Pinto,Inderbir Singh,Dinesh K. Chellappan,Kamal Dua

General Review Article

Recent Developments in the Synthesis of Tetrazoles and their Pharmacological Relevance

Journal: Current Organic Chemistry
Volume: 25 Issue: 3 Year: 2021 Page: 388-403
Author(s): Socorro Leyva-Ramos,Jaime Cardoso-Ortiz

Research Article

Improved 3D-QSAR Prediction by Multiple Conformational Alignments and Molecular Docking Studies to Design and Discover HIV-I Protease Inhibitors

Journal: Current HIV Research
Volume: 19 Issue: 2 Year: 2021 Page: 154-171
Author(s): Paresh K. Patel,Hardik G. Bhatt

Research Article

Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes

Journal: Medicinal Chemistry
Volume: 17 Issue: 0 Year: 2021 Page: 1-19
Author(s): Thiago M. de Aquino,Paulo H. B. França,Érica E. E. S. Rodrigues,Igor J. S. Nascimento,Paulo F. S. Santos-Júnior,Pedro G. V. Aquino,Mariana S. Santos,Aline C. Queiroz,Morgana V. Araújo,Magna S. Alexandre-Moreira,Raiza R. L. Rodrigues,Klinger A. F. Rodrigues,Johnnatan D. Freitas,Jacques Bricard,Mario R. Meneghetti,Jean-Jacques Bourguignon,Martine Schmitt,Edeildo F. da Silva-Júnior,João X. de Araújo-Júnior

Research Article open access plus

New C2- and N3-Modified Thieno[2,3-d]Pyrimidine Conjugates with Cytotoxicity in the Nanomolar Range

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-12
Author(s): Anelia Ts. Mavrova,Stefan Dimov,Denitsa Yancheva,Miroslav Rangelov,Diana Wesselinova,Emilia Naydenova

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