Search Result "constitutive androstane receptor"


Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 7 Issue: 2 Year: 2009 Page: 81-105
Author(s): Juan P. Hernandez, Linda C. Mota, William S. Baldwin

Xenobiotic-Sensing Nuclear Receptors CAR and PXR as Drug Targets in Cholestatic Liver Disease

Journal: Current Drug Targets
Volume: 10 Issue: 1 Year: 2009 Page: 1156-1163
Author(s): Satoru Kakizaki, Daichi Takizawa, Hiroki Tojima, Yuichi Yamazaki, Masatomo Mori

Investigation of the CYP2C9 Induction Profile in Human Hepatocytes by Combining Experimental and Modelling Approaches

Journal: Current Drug Metabolism
Volume: 10 Issue: 1 Year: 2009 Page: 1066-1074
Author(s): Ales Belic, Manna Temesvari, Krisztina Kohalmy, Radim Vrzal, Zdenek Dvorak, Damjana Rozman, Katalin Monostory

Pregnane X Receptor and its Potential Role in Drug Resistance in Cancer Treatment

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 1 Year: 2009 Page: 19-27
Author(s): Yakun Chen, Daotai Nie

Expression, Function and Regulation of Mouse Cytochrome P450 Enzymes: Comparison With Human Cytochrome P450 Enzymes

Journal: Current Drug Metabolism
Volume: 10 Issue: 1 Year: 2009 Page: 1151-1183
Author(s): E. G. Hrycay, S. M. Bandiera

The Transcriptional Regulation of the Human CYP2C Genes

Journal: Current Drug Metabolism
Volume: 10 Issue: 6 Year: 2009 Page: 567-578
Author(s): Yuping Chen, Joyce A. Goldstein

Substrate Specificity, Regulation, and Polymorphism of Human Cytochrome P450 2B6

Journal: Current Drug Metabolism
Volume: 10 Issue: 7 Year: 2009 Page: 730-753
Author(s): Sui-Lin Mo, Ya-He Liu, Wei Duan, Ming Qian Wei, Jagat R. Kanwar, Shu-Feng Zhou

Human CYP2C8: Structure, Substrate Specificity, Inhibitor Selectivity, Inducers and Polymorphisms

Journal: Current Drug Metabolism
Volume: 10 Issue: 9 Year: 2009 Page: 1009-1047
Author(s): Xin-Sheng Lai, Li-Ping Yang, Xiao-Tian Li, Jun-Ping Liu, Zhi-Wei Zhou, Shu-Feng Zhou

Transcriptional Regulation of Cytochrome P450 Genes by the Nuclear Receptor Hepatocyte Nuclear Factor 4-Alpha

Journal: Current Drug Metabolism
Volume: 10 Issue: 5 Year: 2009 Page: 508-519
Author(s): Ramiro Jover, Marta Moya, M. Jose Gomez-Lechon

Substrates, Inducers, Inhibitors and Structure-Activity Relationships of Human Cytochrome P450 2C9 and Implications in Drug Development

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2009 Page: 3480-3675
Author(s): S.-F. Zhou, Z.-W. Zhou, L.-P. Yang, J.-P. Cai

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