Search Result "dihydrofolate reductase"


Interactions of Pyrimidine Derivatives with Dihydrofolate Reductase and Thymidylate Synthase: Directions Toward Combating toxoplasmosis

Journal: Current Bioactive Compounds
Volume: 9 Issue: 2 Year: 2013 Page: 153-166
Author(s): Letícia C. Assis,Letícia Santos-Garcia,Teodorico C. Ramalho,Elaine F. F. da Cunha

Synthesis and Biological Evaluation of Novel Antifolate Analogs as Potential Anticancer Treatment

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 2 Year: 2013 Page: 364-372
Author(s): Dan F. Stoicescu,Maria Rotaru

Methylenetetrahydrofolate Reductase: Biochemical Characterization and Medical Significance

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 2574-2593
Author(s): Elizabeth E. Trimmer

Design and In vitro Validation of Multivalent Dendrimer Methotrexates as a Folate-targeting Anticancer Therapeutic

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 37 Year: 2013 Page: 6594-6605
Author(s): Thommey P. Thomas,Melvin Joice,Madhuresh Sumit,Justin E. Silpe,Alina Kotlyar,Sophia Bharathi,Jolanta Kukowska-Latallo,James R. Baker,Seok Ki Choi

Biosynthetic and Metabolic Alterations in Cancer Growth

Journal: Current Angiogenesis (Discontinued)
Volume: 2 Issue: 2 Year: 2013 Page: 149-156
Author(s): Jie Zheng,Peng Gao

A Decade of Plasmodium falciparum Metabolic Pathways of Therapeutic Interest to Develop New Selective Antimalarial Drugs

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 9 Year: 2013 Page: 1340-1347
Author(s): Anita Cohen,Aurélien Dumètre,Nadine Azas

Protonation States and Conformational Ensemble in Ligand-based QSAR Modeling

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 2 Year: 2013 Page: 4323-4329
Author(s): Pier G. De Benedetti

Update on Diagnostic and Treatment of Uncomplicated and Complicated Malaria in Adults and Selected Vulnerable Populations

Journal: Infectious Disorders - Drug Targets
Volume: 13 Issue: 4 Year: 2013 Page: 278-291
Author(s): Philip Botha,Emmanuel Bottieau,Olalekan Uthman,Ude Obike,Jean B. Nachega

Key Targets and Relevant Inhibitors for the Drug Discovery of Tuberculosis

Journal: Current Drug Targets
Volume: 14 Issue: 6 Year: 2013 Page: 676-699
Author(s): Xiuming Xiong, Zhijian Xu, Zhuo Yang, Yingtao Liu, Di Wang, Mei Dong, Emily J. Parker, Weiliang Zhu

Structural and Functional Role of Gly281 in L-asparaginase from Erwinia carotovora

Journal: Protein & Peptide Letters
Volume: 20 Issue: 1 Year: 2013 Page: 1302-1307
Author(s): Georgia A. Kotzia, Nikolaos E. Labrou

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