Search Result "drug discovery and disease."


The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2001 Page: 353-366
Author(s): Gary W. Caldwell, David M. Ritchie, John A. Masucci, William Hageman, Zhengyin Yan

Proteomics as a Tool in the Pharmaceutical Drug Design Process

Journal: Current Pharmaceutical Design
Volume: 7 Issue: 4 Year: 2001 Page: 291-310
Author(s): M. Yosida, J. A. Loo, R. A. Lepley

Update on Antifolate Drugs Targets

Journal: Current Drug Targets
Volume: 2 Issue: 2 Year: 2001 Page: 135-166
Author(s): M. P. Costi, S. Ferrari

Enterohepatic Recirculation A Powerful Incentive for Drug Discovery in the Inosine Monophosphate Dehydrogenase Field

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 1 Issue: 1 Year: 2001 Page: 71-77
Author(s): Christos Papageorgiou

Hepatic Cytochrome P450 Regulation in Disease States

Journal: Current Drug Metabolism
Volume: 2 Issue: 2 Year: 2001 Page: 165-183
Author(s): Po-Yung Cheng, Edward T. Morgan

Helicobacter pylori Current Chemotherapy and New Targets for Drug Design

Journal: Current Pharmaceutical Design
Volume: 7 Issue: 5 Year: 2001 Page: 355-392
Author(s): John S. Williamson

Trypanosomal dUTPases as Potential Targets for Drug Design

Journal: Current Protein & Peptide Science
Volume: 2 Issue: 4 Year: 2001 Page: 389-397
Author(s): Fernando Hidalgo-zarco, Dolores Gonzalez-pacnowska

beta-Amyloid Aggregation Inhibitors for the Treatment of Alzheimer Disease Dream or Reality?

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 1 Issue: 2 Year: 2001 Page: 175-186
Author(s): Patrice Talaga

The Nuclear Receptors FXR and LX alpha Potential Targets for the Development of Drugs Affecting Lipid Metabolism and Neoplastic Diseases

Journal: Current Pharmaceutical Design
Volume: 7 Issue: 4 Year: 2001 Page: 231-259
Author(s): Eric J. Niesor, Jean Flach, Isabelle Lopes-Antoni, Anne Perez, Craig L. Bentzen

Bone Disease - Current Knowledge and Future Prospects

Journal: Current Genomics
Volume: 2 Issue: 2 Year: 2001 Page: 91-124
Author(s): Francesca Lazner, Ernst Wolvetang, Daniel Lazner, Paul Hertzog

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