Search Result "druggability"


Research Article

Exploring the Lapse in Druggability: Sequence Analysis, Structural Dynamics and Binding Site Characterization of K-RasG12C Variant, a Feasible Oncotherapeutics Target

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1540-1550
Author(s): Emmanuel A. Adeniji,Fisayo A. Olotu,Mahmoud E.S. Soliman

Review Article

Toward Small-Molecule Inhibition of Protein–Protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 8 Year: 2018 Page: 674-699
Author(s): Damir Bojadzic,Peter Buchwald

Review Article

Advances in Computational Studies of Potential Drug Targets in Mycobacterium tuberculosis

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1062-1074
Author(s): Subha Mahadevi Alladi

Review Article

Identification of Drug Binding Sites and Action Mechanisms with Molecular Dynamics Simulations

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 2 Year: 2018 Page: 2268-2277
Author(s): Yang Wang,Cecylia Severin Lupala,Haiguang Liu,Xubo Lin

Review Article

Anaplastic Lymphoma Kinase in Glioblastoma: Detection/Diagnostic Methods and Therapeutic Options

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 13 Issue: 2 Year: 2018 Page: 209-223
Author(s): Theodosis Kalamatianos,Despoina Denekou,George Stranjalis,Evangelia Papadimitriou

Review Article

Nanostructured Hyaluronic Acid-based Materials for the Delivery of siRNA

Journal: Current Pharmaceutical Design
Volume: 24 Issue: 2 Year: 2018 Page: 2678-2691
Author(s): Keval Shah,Sunita Chawla,Anuradha Gadeval,Goutham Reddy,Rahul Maheshwari,Kiran Kalia,Rakesh Kumar Tekade

Review Article open access plus

Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 2 Year: 2018 Page: 3256-3271
Author(s): Shikun Yang,Aimei Li,JianWen Wang,Jun Liu,Yachun Han,Wei Zhang,Yan Chun Li,Hao Zhang

Review Article open access plus

Development of MTL-CEBPA: Small Activating RNA Drug for Hepatocellular Carcinoma

Journal: Current Pharmaceutical Biotechnology
Volume: 19 Issue: 8 Year: 2018 Page: 611-621
Author(s): Ryan L. Setten,Helen L. Lightfoot,Nagy A. Habib,John J. Rossi

Overview

Building on Success: A Bright Future for Peptide Therapeutics

Journal: Protein & Peptide Letters
Volume: 25 Issue: 1 Year: 2018 Page: 1044-1050
Author(s): Yvonne Angell,Mandë Holford,Walter H. Moos

Review Article

Improved Protein Toxin Delivery Based on ATTEMPTS Systems

Journal: Current Drug Targets
Volume: 19 Issue: 4 Year: 2018 Page: 380-392
Author(s): Yingzhi Chen,Meng Zhang,Kyoung Ah Min,Huiyuan Wang,Meong Cheol Shin,Feng Li,Victor C. Yang,Yongzhuo Huang

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