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Research Article open access plus

Synthesis and Biological Evaluation of Some Novel Thiophene-bearing Quinazoline Derivatives as EGFR Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 2 Year: 2019 Page: 102-110
Author(s): Min Zou,Bo Jin,Yanrong Liu,Huiping Chen,Zhuangli Zhang,Changzheng Zhang,Zhihong Zhao,Liyun Zheng

Generations of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Battle against Drug Resistant Lung Cancer

Ebook: Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms

Volume: 5 Year: 2019
Author(s): Kenneth K.W. To,Wing-Sum Tong
Doi: 10.2174/97898114051501190501
Research Article

Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7- ones Derivatives as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 8 Year: 2019 Page: 826-834
Author(s): Ao Niu,Yang Wang,Yushe Yang,Jianhai Wei,Jian Ding,Yi Chen,Linjiang Tong,Hua Xie

Research Article

Investigating Structural Requirements of Some Pyrimidine-linked Benzimidazole Derivatives as Anticancer Agents Against MCF-7 Cancerous Cell Line Through the use of 2D and 3D QSARs

Journal: Current Chemical Biology
Volume: 13 Issue: 3 Year: 2019 Page: 232-249
Author(s): Kale Mayura,Khan Sharuk,Hature Jyoti

Review Article

Drug Combinatorial Therapies for the Treatment of KRAS Mutated Lung Cancers

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2128-2142
Author(s): Hao He,Chang Xu,Zhao Cheng,Xiaoying Qian,Lei Zheng

Review Article

Molecular Mechanisms and Targeted Therapies Including Immunotherapy for Non-Small Cell Lung Cancer

Journal: Current Cancer Drug Targets
Volume: 19 Issue: 8 Year: 2019 Page: 595-630
Author(s): Tatsuya Nagano,Motoko Tachihara,Yoshihiro Nishimura

Research Article

Cytotoxicity and Molecular Targeting Study of Novel 2-Chloro-3- substituted Quinoline Derivatives as Antitumor Agents

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 3 Year: 2019 Page: 273-283
Author(s): Mohammed A.M. Massoud,Magda A. El-Sayed,Waleed A. Bayoumi,Basem Mansour

Review Article

Neoadjuvant Therapy is Essential for Resectable Pancreatic Cancer

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 4 Year: 2019 Page: 7196-7211
Author(s): Jin-Zhi Xu,Wen-Quan Wang,Shi-Rong Zhang,Hua-Xiang Xu,Chun-Tao Wu,Zi-Hao Qi,He-Li Gao,Shuo Li,Quan-Xing Ni,Xian-Jun Yu,Liang Liu

Review Article

Do we Need Maintenance Chemotherapy in Advanced NSCLC in the Era of Immune and Targeted Therapy?

Journal: Current Cancer Therapy Reviews
Volume: 15 Issue: 1 Year: 2019 Page: 50-55
Author(s): Ahmed A. Nagy,Omar Abdel Rahman,Heba Abdullah,Ahmed Negida

Review Article

Celecoxib in Cancer Therapy and Prevention – Review

Journal: Current Drug Targets
Volume: 20 Issue: 3 Year: 2019 Page: 302-315
Author(s): Natalia Tołoczko-Iwaniuk,Dorota Dziemiańczyk-Pakieła,Beata Klaudia Nowaszewska,Katarzyna Celińska-Janowicz,Wojciech Miltyk

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