Search Result "mTOR inhibitors"


A Novel Quinoline Based Second-generation mTOR Inhibitor that Induces Apoptosis and Disrupts PI3K-Akt-mTOR Signaling in Human Leukemia HL-60 Cells

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 15 Issue: 10 Year: 2015 Page: 1297-1304
Author(s): Suresh Kumar,Santosh Kumar Guru,Vunnam Venkateswarlu,Fayaz Malik,Ram A. Vishwakarma,Sanghapal D. Sawant,Shashi Bhushan

mTOR: A Novel Therapeutic Target for Diseases of Multiple Systems

Journal: Current Drug Targets
Volume: 16 Issue: 10 Year: 2015 Page: 1107-1132
Author(s): Zhao Zhong Chong

The PI3K-AKt-mTOR Pathway and New Tools to Prevent Acquired Hormone Resistance in Breast Cancer

Journal: Current Pharmaceutical Biotechnology
Volume: 16 Issue: 9 Year: 2015 Page: 804-815
Author(s): Andrea Nicolini,Paola Ferrari,Lucie Kotlarova,Giuseppe Rossi,Pier M. Biava

Mitochondrial Dysfunction and Its Relationship with mTOR Signaling and Oxidative Damage in Autism Spectrum Disorders

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 15 Issue: 5 Year: 2015 Page: 373-389
Author(s): Kunio Yui,Atsushi Sato,George Imataka

Targeting the PI3K/AKT/mTOR Signaling Pathway in Medulloblastoma

Journal: Current Molecular Medicine
Volume: 15 Issue: 1 Year: 2015 Page: 82-93
Author(s): V. Dimitrova,A. Arcaro

Age-Related Neurodegeneration Prevention Through mTOR Inhibition: Potential Mechanisms and Remaining Questions

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 21 Year: 2015 Page: 2139-2151
Author(s): Jordan B. Jahrling,Remi-Martin Laberge

Ligustrazine Suppresses the Growth of HRPC Cells through the Inhibition of Cap- Dependent Translation Via Both the mTOR and the MEK/ERK Pathways

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 15 Issue: 6 Year: 2015 Page: 764-772
Author(s): Jiaoyan Han,Jiao Song,Xiangyun Li,Ming Zhu,Wei Guo,Wei Xing,Rongshen Zhao,Xiao He,Xiaoping Liu,Shali Wang,Yunyun Li,Hong Huang,Xiang Xu

Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 21 Year: 2015 Page: 2116-2138
Author(s): Caio Henrique Mazucanti,Joao Victor Cabral-Costa,Andrea Rodrigues Vasconcelos,Diana Zukas Andreotti,Cristoforo Scavone,Elisa Mitiko Kawamoto

Multi-Kinase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 6 Year: 2015 Page: 695-712
Author(s): Laura Garuti,Marinella Roberti,Giovanni Bottegoni

Purine Analogues as Kinase Inhibitors: A Review

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 10 Issue: 3 Year: 2015 Page: 308-341
Author(s): Sahil Sharma,Samir Mehndiratta,Sunil Kumar,Jagjeet Singh,Preet M.S. Bedi,Kunal Nepali

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