Search Result "novel imidazo"


Research Article

A Novel Imidazo[1,2-a]pyridine Compound Reduces Cell Viability and Induces Apoptosis of HeLa Cells by p53/Bax-Mediated Activation of Mitochondrial Pathway

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-10
Author(s): Yang Yu,Yanwen Li,Xinjie Yang,Qiuyi Deng,Bin Xu,Hua Cao,Jianwen Mao

Research Article

Novel 4-Oxo-4,10-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxylic Acid Derivatives as HIV-1 Integrase Inhibitors: Synthesis, Docking Studies, Molecular Dynamics Simulation and Biological Activities

Journal: Medicinal Chemistry
Volume: 17 Issue: 9 Year: 2021 Page: 1060-1071
Author(s): Elnaz Ebrahim Zadeh,Rouhollah Vahabpour,Amirreza Dowlati Beirami,Zahra Hajimahdi,Afshin Zarghi

Research Article open access plus

Discovery of Structural Prospects of Imidazo[1,5-a]pyrazine Derivatives as BTK Inhibitors Against Cancer: A Computational Study

Journal: Letters in Drug Design & Discovery
Volume: 18 Issue: 0 Year: 2021 Page: 1-13
Author(s): Amena Ali,Abuzer Ali,Mohamed Jawed Ahsan

Research Article

New Approaches for the Synthesis of Heterocyclic Compounds Corporating Benzo[d]imidazole as Anticancer Agents, Tyrosine, Pim-1 Kinases Inhibitions and their PAINS Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 3 Year: 2021 Page: 279-294
Author(s): Rafat M. Mohareb,Yara R. Milad,Bahaa M. Mostafa,Reem A. El-Ansary

Research Article

Molecular Modelling, Synthesis and Biological Evaluation of Novel Benzimidazole Derivatives for the Treatment of Breast Cancer

Journal: Current Chinese Chemistry
Volume: 1 Issue: 1 Year: 2021 Page: 11-20
Author(s): Ishan Panchal,Animesh G. Devgirkar,Ashish D. Patel,Afzal Nagani,Chaitali Lad

Research Article

Synthesis, Molecular Docking and Biological Evaluation of Novel Flavone Derivatives as Potential Anticancer Agents Targeting Akt

Journal: Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2021 Page: 158-170
Author(s): Heba M. Abo-Salem,Abdullah A Gibriel,Mohamed E. El Awady,Adel H. Mandour

Review Article

Current Scenario of Acridine Hybrids with Anticancer Potential

Journal: Current Topics in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-14
Author(s): Qihong Zhang,Xia Yu

General Review Article

Synthetic and Biological Attributes of Pyrimidine Derivatives: A Recent Update

Journal: Current Organic Synthesis
Volume: 18 Issue: 0 Year: 2021 Page: 1-36
Author(s): Meenu Devi,Shivangi Jaiswal,Sonika Jain,Navjeet Kaur,Jaya Dwivedi

General Research Article

Machine Learning-based Virtual Screening Strategy Reveals Some Natural Compounds As Potential PAK4 Inhibitors In Triple Negative Breast Cancer

Journal: Current Proteomics
Volume: 18 Issue: 0 Year: 2021 Page: 1-18
Author(s): Toyin Mary Fadipe,Emmanuel Ayo Oluwarotimi,Babatomiwa Kikiowo,Olusola Olalekan Elekofehinti,Opeyemi Iwaloye

Review Article

Imidazole Scaffold Based Compounds in the Development of Therapeutic Drugs

Journal: Current Topics in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-15
Author(s): Fanjie Hu,Lina Zhang,Kutty Selva Nandakumar,Kui Cheng

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