Search Result "optimization"


The New Pre-Preclinical Paradigm: Compound Optimization in Early and Late Phase Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2001 Page: 353-366
Author(s): Gary W. Caldwell, David M. Ritchie, John A. Masucci, William Hageman, Zhengyin Yan

The Importance of Drug Delivery to Optimize the Effects of Bone Morphogenetic Proteins During Periodontal Regeneration

Journal: Current Pharmaceutical Biotechnology
Volume: 2 Issue: 2 Year: 2001 Page: 131-142
Author(s): Gaston N. King

High-speed Molecular Mechanics Searches for Optimal DNA Interaction Sites

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 4 Issue: 8 Year: 2001 Page: 707-717
Author(s): Ingrid Lafontaine, Richard Lavery

Filamentous Fungi Potentially Useful Catalysts for the Biohydroxylations of Non-Activated Carbon Centers

Journal: Current Organic Chemistry
Volume: 5 Issue: 4 Year: 2001 Page: 439-470
Author(s): Leslie R. Lehman, Jon D. Stewart

Assessing the Potential Toxicity of New Pharmaceuticals

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 4 Year: 2001 Page: 233-245
Author(s): Dale E. Johnson, Grushenka H.I. Wolfgang

Characteristics of a New Antifungal Protein from Ginkgo biloba L.

Journal: Protein & Peptide Letters
Volume: 8 Issue: 3 Year: 2001 Page: 209-216
Author(s): Hu Huang, Jin-fei Xu, Zhen-zhen Gong

The Linear Interaction Energy Method for Predicting Ligand Binding Free Energies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 4 Issue: 8 Year: 2001 Page: 613-626
Author(s): Johan Aqvist, John Marelius

Discovery of the Factor Xa Inhibitor, ZK 807834 (CI-1031)

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 2 Year: 2001 Page: 121-136
Author(s): David R. Light, William J. Guilford

DNA Vaccines.

Journal: Current Molecular Medicine
Volume: 1 Issue: 2 Year: 2001 Page: 217-243
Author(s): Arturo Reyes-Sandoval, Hildegund C.J. Ertl

The Design and Synthesis of Noncovalent Factor Xa Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 1 Issue: 2 Year: 2001 Page: 137-149
Author(s): M. L. Quan, R. R. Wexler

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