Search Result "pharmacodynamics and pharmacokinetics"


How Much Gets there and What Does it Do?: The Need for Better Pharmacokinetic and Pharmacodynamic Endpoints in Contemporary Drug Discovery and Development

Journal: Current Pharmaceutical Design
Volume: 9 Issue: 1 Year: 2003 Page: 891-902
Author(s): Paul Workman

Genetic Polymorphism of Organic Anion and Cation Transporters: Pharmacokinetic and Pharmacodynamic Consequences in Pharmacotherapy

Journal: Current Pharmacogenomics
Volume: 1 Issue: 4 Year: 2003 Page: 245-257
Author(s): Hiroshi Takane, Ichiro Ieiri, Kenji Otsubo

Utility of Mdr1-Gene Deficient Mice in Assessing the Impact of P-glycoprotein on Pharmacokinetics and Pharmacodynamics in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 4 Issue: 4 Year: 2003 Page: 272-291
Author(s): Cuiping Chen, Xingrong Liu, Bill J. Smith

Recent Trends in the Use of Polysaccharides for Improved Delivery of Therapeutic Agents: Pharmacokinetic and Pharmacodynamic Perspectives

Journal: Current Pharmaceutical Biotechnology
Volume: 4 Issue: 5 Year: 2003 Page: 283-302
Author(s): Reza Mehvar

Classic Histamine H1 Receptor Antagonists: A Critical Review of their Metabolic and Pharmacokinetic Fate from a Birds Eye View

Journal: Current Drug Metabolism
Volume: 4 Issue: 2 Year: 2003 Page: 105-129
Author(s): A. Sharma, B. A. Hamelin

The Clinical Applications of Heat Shock Protein Inhibitors in Cancer - Present and Future

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 385-390
Author(s): Udai Banerji, Ian Judson, Paul Workman

Reaction Phenotyping in Drug Discovery: Moving Forward with Confidence?

Journal: Current Drug Metabolism
Volume: 4 Issue: 6 Year: 2003 Page: 527-534
Author(s): J. Andrew Williams, Susan I. Hurst, Jonathan Bauman, Barry C. Jones, Ruth Hyland, John P. Gibbs, R. Scott Obach, Simon E. Ball

The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 349-358
Author(s): Luke Whitesell, Rochelle Bagatell, Ryan Falsey

Drug Metabolism and Drug Interactions: Application and Clinical Value of In Vitro Models

Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 423-459
Author(s): Karthik Venkatakrishnan, Lisa L. von Moltke, R. Scott Obach, David J. Greenblatt

Development and Potential Utility of Dual and Triple NK Receptor Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 3 Issue: 1 Year: 2003 Page: 1410-1422
Author(s): Charles A. Rizzo, John C. Anthes, Michel R. Corboz, Richard W. Chapman, Neng-Yang Shih, Greg A. Reichard, Kwokei J. Ng, John A. Hey

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