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New Strategies in Drug Development Focusing on the Anti-Protease-Protease Balance in Alpha-1 Antitrypsin Deficiency

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 9 Issue: 4 Year: 2010 Page: 314-329
Author(s): Emer P. Reeves, Sonya Cosgrove, David A. Bergin, Catherine M. Greene, Noel G. McElvaney

Computational Methods for De novo Protein Design and its Applications to the Human Immunodeficiency Virus 1, Purine Nucleoside Phosphorylase, Ubiquitin Specific Protease 7, and Histone Demethylases

Journal: Current Drug Targets
Volume: 11 Issue: 3 Year: 2010 Page: 264-278
Author(s): M. L. Bellows, C. A. Floudas

Chemical Modifications Designed to Improve Peptide Stability: Incorporation of Non-Natural Amino Acids, Pseudo-Peptide Bonds, and Cyclization

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 2 Year: 2010 Page: 3185-3203
Author(s): Luca Gentilucci, Rossella De Marco, Lucia Cerisoli

Small Molecule Inhibitors of Peptidylprolyl cis/trans Isomerase

Journal: Current Enzyme Inhibition
Volume: 6 Issue: 1 Year: 2010 Page: 46-53
Author(s): Tadashi Mori, Takafumi Uchida

Peptidase Inhibitors as a Possible Therapeutic Strategy for Chagas Disease

Journal: Current Enzyme Inhibition
Volume: 6 Issue: 4 Year: 2010 Page: 183-194
Author(s): Giseli Capaci Rodrigues, Alcino Palermo Aguiar, Joao Lidio da Silva Goncalves Vianez, Andrew Macrae, Ana Cristina Nogueira de Melo, Alane Beatriz Vermelho

Aminopeptidases of Malaria Parasites: New Targets for Chemotherapy

Journal: Infectious Disorders - Drug Targets
Volume: 10 Issue: 3 Year: 2010 Page: 217-225
Author(s): Katharine R. Trenholme, Christopher L. Brown, Tina S. Skinner-Adams, Colin Stack, Jonathan Lowther, Joyce To, Mark W. Robinson, Sheila M. Donnelly, John P. Dalton, Donald L. Gardiner

Applications and Modifications of 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid (Tic) in Peptides and Peptidomimetics Design and Discovery

Journal: Current Protein & Peptide Science
Volume: 11 Issue: 8 Year: 2010 Page: 752-758
Author(s): Yingjie Zhang, Hao Fang, Wenfang Xu

L-Valine and L-Proline - Solid-State IR-LD Spectroscopic Study

Journal: Protein & Peptide Letters
Volume: 17 Issue: 3 Year: 2010 Page: 347-350
Author(s): A. G. Chapkanov, S. Y. Zareva

Interaction and Structural Modification of Topoisomerase IIα by Peptidyl Prolyl Isomerase, pin1: An In Silico Study

Journal: Protein & Peptide Letters
Volume: 17 Issue: 2 Year: 2010 Page: 151-163
Author(s): Rohit Mathur, Shubhanker Suman, Nicolas Beaume, Mashook Ali, Anant N. Bhatt, Madhu Chopra, Daman Saluja, Anil K. Mishra, Sudhir Chandna, Pramesh N. Kapoor, Bilikere S. Dwarakanath

Up-Regulation of Hypoxia-Inducible Factor (HIF)-1α and HIF-Target Genes in Cortical Neurons by the Novel Multifunctional Iron Chelator Anti-Alzheimer Drug, M30

Journal: Current Alzheimer Research
Volume: 7 Issue: 4 Year: 2010 Page: 300-306
Author(s): Y. Avramovich-Tirosh, O. Bar-Am, T. Amit, M.B.H. Youdim, O. Weinreb

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