Search Result "topoisomerase"


Targeting DNA Topoisomerase I with Non-Camptothecin Poisons

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 8 Year: 2012 Page: 1238-1257
Author(s): G. L. Beretta, V. Zuco, P. Perego, N. Zaffaroni

Flavonoids Acting on DNA Topoisomerases: Recent Advances and Future Perspectives in Cancer Therapy

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 3 Year: 2012 Page: 5287-5293
Author(s): P. Russo, A. Del Bufalo, A. Cesario

Cancer Resistance to Type II Topoisomerase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3900-3906
Author(s): P. Pilati, D. Nitti, S. Mocellin

Methylenedioxy- and Ethylenedioxy-Fused Indolocarbazoles: Potent Human Topoisomerase I Inhibitors and Antitumor Agents

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 9 Year: 2012 Page: 1117-1131
Author(s): David E. Zembower,Yongping Xie,Ali Koohang,Mary J. Kuffel,Matthew M. Ames,Yasheen Zhou,Rama Mishra,Aye Aye Mar,Michael T. Flavin,Ze-Qi Xu

DNA Repair and Resistance to Topoisomerase I Inhibitors: Mechanisms, Biomarkers and Therapeutic Targets

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3874-3885
Author(s): M. Alagoz, D. C. Gilbert, S. El-Khamisy, A. J. Chalmers

Synthesis, Docking and Biological Evaluation of Some Novel 5-bromo-2- (5-aryl-1,3,4-thiadiazol-2-yl)isoindoline-1,3-dione Derivatives Targeting ATP-binding Site of Topoisomerase II

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 7 Year: 2012 Page: 668-675
Author(s): Ankur Gupta,Priya Singh,Bhagyashree Kamble,Aditi Kulkarni,Moola Joghee Nanjan Chandrasekar

Delivery Methods of Camptothecin and Its Hydrosoluble Analogue Irinotecan for Treatment of Colorectal Cancer

Journal: Current Drug Delivery
Volume: 9 Issue: 2 Year: 2012 Page: 122-131
Author(s): Adriano Mollica, Azzurra Stefanucci, Federica Feliciani, Ivana Cacciatore, Catia Cornacchia, Francesco Pinnen

SAR Analysis of New Dual Targeting Fluoroquinolones. Implications of the Benzenesulfonyl Group

Journal: Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2012 Page: 349-360
Author(s): Marcelo J. Nieto,Adriana B. Pierini,Nidhi Singh,Christopher R. McCurdy,Ruben H. Manzo,aria R. Mazzieri

In Vitro Synergistic Interaction between DTA0100 and Radiation in Human Cancer Cell Lines

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 988-993
Author(s): Elisa Bordon,Leticia G. Leon,Carla Rios-Luci,Pedro C. Lara,Jose M. Padron

Novel Approaches in the Synthesis of Batracylin and Its Analogs: Rebirth of an Old Player?

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 4475-4487
Author(s): K. Dzierzbicka, W. Januchta, A. Skladanowski

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