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Endocrine, Metabolic & Immune Disorders-Drug Targets
(Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders)
ISSN (Print): 1871-5303
ISSN (Online): 2212-3873
VOLUME: 14
ISSUE: 1
DOI: 10.2174/1871530314666140121145045









Breast-Milk Characteristics Protecting Against Allergy

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Author(s): Federica Minniti, Pasquale Comberiati, Daniel Munblit, Giorgio L. Piacentini, Elisa Antoniazzi, Laura Zanoni, Attilio L. Boner and Diego G. Peroni
Pages 9-15 (7)
Abstract:
Breast milk and colostrum are the first feeding sources for a child, providing nutrients, growth factors and immunological components, which are crucial for the newborn’s correct development and health. Length of exclusive breastfeeding and time of solid foods introduction is a key factor that may influence allergy development. There is an emerging evidence of a relationship between breastfeeding, milk composition and lower risk of chronic diseases, such as diabetes, obesity, hypertension and allergies. This review examines current evidence regarding humoral and cellular characteristics of breast-milk, and potential role of environment, maternal diet and breastfeeding on the allergy development in children.
Keywords:
Allergy, atopy, breast-milk, breastfeeding, cytokines, environment, immunoglobulin, nutrients.
Affiliation:
Department of Pediatrics, G.B. Rossi Polyclinic, Piazzale L.A. Scuro 10, 37134 Verona, Italy.