Abstract
Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.
Keywords: Alzheimer disease, cerebral blood flow, disease progression, hemodynamics, risk factors, transcranial Doppler.
CNS & Neurological Disorders - Drug Targets
Title:Vascular Contribution to Alzheimer Disease: Predictors of Rapid Progression
Volume: 12 Issue: 4
Author(s): Marina Diomedi and Giulia Misaggi
Affiliation:
Keywords: Alzheimer disease, cerebral blood flow, disease progression, hemodynamics, risk factors, transcranial Doppler.
Abstract: Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.
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Cite this article as:
Diomedi Marina and Misaggi Giulia, Vascular Contribution to Alzheimer Disease: Predictors of Rapid Progression, CNS & Neurological Disorders - Drug Targets 2013; 12 (4) . https://dx.doi.org/10.2174/1871527311312040015
DOI https://dx.doi.org/10.2174/1871527311312040015 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
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