Abstract
Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease resulting from multiplex causes. Evidence indicates that stem/progenitor cells might play a key role in IPF pathogenesis and repair, which may provide some novel potential strategies for the future treatment of IPF. In this review, we first summarize the current understanding of the relationship between stem cells and IPF and then review the advancements made in recent clinical trials using stem/progenitor cells, especially mesenchymal stem cells, in treating IPF and their interpretations.
Keywords: Embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, pulmonary fibrosis, treatment.
Current Stem Cell Research & Therapy
Title:Stem Cell and Idiopathic Pulmonary Fibrosis: Mechanisms and Treatment
Volume: 10 Issue: 6
Author(s): Ming Liu, Dunqiang Ren, Dong Wu, Jian Zheng and Wenwei Tu
Affiliation:
Keywords: Embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, pulmonary fibrosis, treatment.
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease resulting from multiplex causes. Evidence indicates that stem/progenitor cells might play a key role in IPF pathogenesis and repair, which may provide some novel potential strategies for the future treatment of IPF. In this review, we first summarize the current understanding of the relationship between stem cells and IPF and then review the advancements made in recent clinical trials using stem/progenitor cells, especially mesenchymal stem cells, in treating IPF and their interpretations.
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Cite this article as:
Liu Ming, Ren Dunqiang, Wu Dong, Zheng Jian and Tu Wenwei, Stem Cell and Idiopathic Pulmonary Fibrosis: Mechanisms and Treatment, Current Stem Cell Research & Therapy 2015; 10 (6) . https://dx.doi.org/10.2174/1574888X10666150519092639
DOI https://dx.doi.org/10.2174/1574888X10666150519092639 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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