Abstract
Functional biomaterials able to sense and respond to biotic and abiotic stimuli are currently clustered in the category of smart materials. Polymers represent the most investigated class of materials able to change different morphological, functional, architectural and biological properties as a feedback to an external inducing element. Although very useful in most industrial, biotechnological and ecological approaches, biopolymers bring important and intriguing impact in medicine. Numerous applications, ranging from tissue engineering to drug delivery have been recently emerged as a result of the technological progress made in the field of polymer engineering. Most interesting approaches refer to the development of intelligent targeting approaches and the design of tailored biopolymeric scaffolds utilized in therapy. The purpose of this review paper is to bring together and discuss the most recent knowledge regarding applications of smart biopolymers in biomedical scaffolding and drug delivery. Current progress made on the field of tissue engineering, cancer therapy and alternative antimicrobial approaches are highlighted.
Keywords: Smart polymers, drug delivery, intelligent scaffolding, cancer therapy, alternative antimicrobials.
Current Organic Chemistry
Title:Biopolymers Tailored For Intelligent Scaffolding and Drug Delivery
Volume: 20 Issue: 28
Author(s): Lia-Mara Ditu, Veronica Lazar, Alexandru M. Grumezescu and Alina M. Holban
Affiliation:
Keywords: Smart polymers, drug delivery, intelligent scaffolding, cancer therapy, alternative antimicrobials.
Abstract: Functional biomaterials able to sense and respond to biotic and abiotic stimuli are currently clustered in the category of smart materials. Polymers represent the most investigated class of materials able to change different morphological, functional, architectural and biological properties as a feedback to an external inducing element. Although very useful in most industrial, biotechnological and ecological approaches, biopolymers bring important and intriguing impact in medicine. Numerous applications, ranging from tissue engineering to drug delivery have been recently emerged as a result of the technological progress made in the field of polymer engineering. Most interesting approaches refer to the development of intelligent targeting approaches and the design of tailored biopolymeric scaffolds utilized in therapy. The purpose of this review paper is to bring together and discuss the most recent knowledge regarding applications of smart biopolymers in biomedical scaffolding and drug delivery. Current progress made on the field of tissue engineering, cancer therapy and alternative antimicrobial approaches are highlighted.
Export Options
About this article
Cite this article as:
Ditu Lia-Mara, Lazar Veronica, Grumezescu M. Alexandru and Holban M. Alina, Biopolymers Tailored For Intelligent Scaffolding and Drug Delivery, Current Organic Chemistry 2016; 20 (28) . https://dx.doi.org/10.2174/1385272820666160511103622
DOI https://dx.doi.org/10.2174/1385272820666160511103622 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
A Concise Review on Multidimensional Silver Nanoparticle Health Aids and Threats
Current Drug Therapy Recent Patents on Genes and Gene Sequences Useful for Developing Breast Cancer Detection Systems
Recent Patents on DNA & Gene Sequences Neuropeptides as Autocrine Growth Factors in Cancer Cells
Current Pharmaceutical Design Signal Transduction Pathways Provide Opportunities to Enhance HDL and apoAI-Dependent Reverse Cholesterol Transport
Current Pharmaceutical Biotechnology Nitric Oxide Synthase and Cyclooxygenase Pathways: A Complex Interplay in Cellular Signaling
Current Medicinal Chemistry Simple and General Criterion for “in silico” Screening of Candidate HIV Drugs
Current Pharmaceutical Biotechnology Thromboembolic Events in Patients Treated with Anti-Angiogenic Drugs
Current Vascular Pharmacology Meet Our Editorial Board Member
Current Drug Delivery Modulating Mitochondria-Mediated Apoptotic Cell Death through Targeting of Bcl-2 Family Proteins
Recent Patents on DNA & Gene Sequences Synthesis of Daumone Derivatives and their Antiangiogenic Activities on Chorioallantoic Membrane
Medicinal Chemistry Editorial (Moving Beyond Our Mutual Ignorance. Or, How would Engaging the Public Benefit the Personalized Medicine Community?)
Current Pharmacogenomics and Personalized Medicine Changing Faces of Transcriptional Regulation Reflected by Zic3
Current Genomics Phage-based Nanomedicines as New Immune Therapeutic Agents for Breast Cancer
Current Pharmaceutical Design Targeting the Ribosome Biogenesis Key Molecule Fibrillarin to Avoid Chemoresistance
Current Medicinal Chemistry Organophotoredox Catalysis: Visible-light-induced Multicomponent Synthesis of Chromeno[4, 3-b]chromene and Hexahydro-1H-xanthene Derivatives
Current Organocatalysis Reviewing the Cardiovascular Complications of HIV Infection After the Introduction of Highly Active Antiretroviral Therapy
Current Drug Targets - Cardiovascular & Hematological Disorders Meet Our Editorial Board Member
Current Drug Targets Guanylate Cyclase C: A Current Hot Target, from Physiology to Pathology
Current Medicinal Chemistry The Common Mycobacterial Antigens and their Importance in the Treatment of Disease
Current Pharmaceutical Design Photosensitizers for Photodynamic Therapy: Photochemistry in the Service of Oncology
Current Pharmaceutical Design