Abstract
The more significant bioactivities of a variety of semicarbazones (anti-protozoa, anticonvulsant) and thiosemicarbazones (antibacterial, antifungal, antitumoral, antiviral) and their metal complexes are reviewed together with proposed mechanisms of action and structure-activity relationships. Clinical or potential pharmacological applications of these versatile compounds are discussed.
Keywords: Semicarbazones, thiosemicarbazones, biological activity, pharmacological applications, bioactive metal complexes, mechanisms of action
Mini-Reviews in Medicinal Chemistry
Title: The Wide Pharmacological Versatility of Semicarbazones, Thiosemicarbazones and Their Metal Complexes
Volume: 4 Issue: 1
Author(s): H. Beraldo and D. Gambinob
Affiliation:
Keywords: Semicarbazones, thiosemicarbazones, biological activity, pharmacological applications, bioactive metal complexes, mechanisms of action
Abstract: The more significant bioactivities of a variety of semicarbazones (anti-protozoa, anticonvulsant) and thiosemicarbazones (antibacterial, antifungal, antitumoral, antiviral) and their metal complexes are reviewed together with proposed mechanisms of action and structure-activity relationships. Clinical or potential pharmacological applications of these versatile compounds are discussed.
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Cite this article as:
H. Beraldo and D. Gambinob , The Wide Pharmacological Versatility of Semicarbazones, Thiosemicarbazones and Their Metal Complexes, Mini-Reviews in Medicinal Chemistry 2004; 4 (1) . https://dx.doi.org/10.2174/1389557043487484
DOI https://dx.doi.org/10.2174/1389557043487484 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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