Abstract
A critical mechanism to maintain urinary continence in women and men is the striated muscle sphincter (rhabdosphincter) that forms a ring around the mid urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We hereby review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells.
Keywords: Stress urinary incontinence, urethra, stem cell therapy
Current Stem Cell Research & Therapy
Title: Cellular Therapy for Treatment of Stress Urinary Incontinence
Volume: 5 Issue: 1
Author(s): Klaudia Stangel-Wojcikiewicz, Stec Malgorzata, Dmitriy Nikolavsky and Michael B. Chancellor
Affiliation:
Keywords: Stress urinary incontinence, urethra, stem cell therapy
Abstract: A critical mechanism to maintain urinary continence in women and men is the striated muscle sphincter (rhabdosphincter) that forms a ring around the mid urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We hereby review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells.
Export Options
About this article
Cite this article as:
Stangel-Wojcikiewicz Klaudia, Malgorzata Stec, Nikolavsky Dmitriy and Chancellor B. Michael, Cellular Therapy for Treatment of Stress Urinary Incontinence, Current Stem Cell Research & Therapy 2010; 5 (1) . https://dx.doi.org/10.2174/157488810790442840
DOI https://dx.doi.org/10.2174/157488810790442840 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Proteomic Analysis of Phosphorylation in the Brain
Current Proteomics NbCl5 as an Expeditious Catalyst for the Synthesis of Quinoxalinyl and Dibenzodioxepinyl Phosphonates/Phosphinates via Michaelis-Arbuzov Reaction and their Biological Evaluation
Letters in Organic Chemistry Functionalization of Phenols Using a Biomimetic Couple of Sodium Nitrite/Hydrogen Peroxide in an Acidic Medium
Current Organic Chemistry Therapeutic Monitoring of Plasma Digoxin for COVID-19 Patients Using a Simple UPLC-MS/MS Method
Current Pharmaceutical Analysis Radiotracers for Molecular Imaging of Cyclooxygenase-2 (COX-2) Enzyme
Current Medicinal Chemistry Therapeutic Effect of Ribbon-Type Nuclear Factor-κB Decoy Oligonucleotides in a Rat Model of Inflammatory Bowel Disease
Current Gene Therapy Poly(lactide-co-glycolide)-based Micro and Nanoparticles for the Controlled Drug Delivery of Vitamins
Current Nanoscience In Vivo Tumor Secretion Probing Via Ultrafiltration and Tissue Chamber:Implication for Anti-Cancer Drugs Targeting Secretome
Recent Patents on Anti-Cancer Drug Discovery DHODH Hot Spots: An Underexplored Source to Guide Drug Development Efforts
Current Topics in Medicinal Chemistry Natural Products in Drug Discovery - Concepts and Approaches for Tracking Bioactivity
Current Organic Chemistry Genome Projects and the Functional-Genomic Era
Combinatorial Chemistry & High Throughput Screening Nitric Oxide Induced Damage and Preventive Effect of Curcumin and Quercetin on Buffalo Brain Cystatin
Current Proteomics Plasma Surface Treatment and Grafting of Nano-Gold Surface for Immobilization of Chitosan
Current Nanoscience Effects of Spices (Saffron, Rosemary, Cinnamon, Turmeric and Ginger) in Alzheimer's Disease
Current Alzheimer Research Isolation, Synthesis and Biomimetic Reactions of Metalloporphyrinoids in Ionic Liquids
Current Organic Synthesis Role of Hepcidin-25 in Chronic Kidney Disease: Anemia and Beyond
Current Medicinal Chemistry Copanlisib: Novel PI3K Inhibitor for the Treatment of Lymphoma
Anti-Cancer Agents in Medicinal Chemistry α(N)-Heterocyclic Thiosemicarbazones: Iron Chelators that are Promising for Revival of Gallium in Cancer Chemotherapy
Anti-Cancer Agents in Medicinal Chemistry Luminescent Quantum Dots: A Very Attractive and Promising Tool in Biomedicine
Current Medicinal Chemistry Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment
Recent Patents on Anti-Cancer Drug Discovery