Abstract
The epidermal growth factor receptors (EGFRs) belong to the ErbB family of receptor tyrosine kinases (TKs) involved in the proliferation of normal and malignant cells. EGFR has attracted considerable attention as a target for cancer therapy. This article considers various functional roles of EGFR-based systems that are relevant for the early detection and staging of cancers overexpressing EGFR.
Keywords: EGFR, tumor, imaging, targeting, peptide radiopharmaceutical, TUMORS, cancer
Current Radiopharmaceuticals
Title: Epidermal Growth Factor Receptors: A Functional Perspective
Volume: 5 Issue: 1
Author(s): Petar M. Mitrasinovic
Affiliation:
Keywords: EGFR, tumor, imaging, targeting, peptide radiopharmaceutical, TUMORS, cancer
Abstract: The epidermal growth factor receptors (EGFRs) belong to the ErbB family of receptor tyrosine kinases (TKs) involved in the proliferation of normal and malignant cells. EGFR has attracted considerable attention as a target for cancer therapy. This article considers various functional roles of EGFR-based systems that are relevant for the early detection and staging of cancers overexpressing EGFR.
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Cite this article as:
M. Mitrasinovic Petar, Epidermal Growth Factor Receptors: A Functional Perspective, Current Radiopharmaceuticals 2012; 5 (1) . https://dx.doi.org/10.2174/1874471011205010029
DOI https://dx.doi.org/10.2174/1874471011205010029 |
Print ISSN 1874-4710 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-4729 |
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