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Current Chemical Biology


ISSN (Print): 2212-7968
ISSN (Online): 1872-3136

Review Article

Understanding Molecular Process and Chemotherapeutics for the Management of Breast Cancer

Author(s): Abhishek Kumar, Neeraj Masand and Vaishali M. Patil*

Volume 15, Issue 1, 2021

Published on: 28 July, 2020

Page: [69 - 84] Pages: 16

DOI: 10.2174/2212796814999200728185759

Price: $65


Breast cancer is the most common and highly heterogeneous neoplastic disease comprised of several subtypes with distinct molecular etiology and clinical behaviours. The mortality observed over the past few decades and the failure in eradicating the disease is due to the lack of specific etiology, molecular mechanisms involved in the initiation and progression of breast cancer. Understanding of the molecular classes of breast cancer may also lead to new biological insights and eventually to better therapies. The promising therapeutic targets and novel anti-cancer approaches emerging from these molecular targets that could be applied clinically in the near future are being highlighted. In addition, this review discusses some of the details of current molecular classification and available chemotherapeutics.

Keywords: Breast cancer, molecular mechanism, breast cancer types, therapeutic targets, carcinoma, chemotherapeutics.

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