Login Register Cart 0
Review Article

探索痴呆和虚弱管理的最新趋势：专注于诊断和治疗

卷 29, 期 32, 2022

发表于: 19 July, 2022

页: [5289 - 5314] 页: 26

弟呕挨: 10.2174/0929867329666220408102051

价格: $65

摘要

痴呆和虚弱会增加老年人的健康逆境，这是越来越引起研究兴趣的话题。虚弱被认为是一种与年龄相关的生物综合征。虚弱的患者最终可能会在多个系统中出现多种功能障碍，包括中风、短暂性脑缺血发作、血管性痴呆、帕金森病、阿尔茨海默病、额颞叶痴呆、路易体痴呆、皮质基底部变性、多系统萎缩、肌萎缩性侧索硬化和克雅氏病。痴呆和虚弱的患者经常出现营养不良和体重减轻。这些患者通常需要严格的营养、药理学和非药理学干预，这对医疗保健提供者来说是一个具有挑战性的问题。从小养成健康的饮食和生活方式可以降低虚弱和痴呆的风险。为了获得最佳治疗，需要包括临床评估、认知筛查、基本实验室评估、结构成像、功能性神经成像和神经心理学测试在内的准确诊断。诊断程序最好应用临床诊断，确定适合治疗的原因和条件。患者的病史、护理者的面谈、体检、认知评估、实验室测试和结构成像应最佳地参与诊断过程。不同类型的体育锻炼可以帮助治疗这些疾病。营养维持是一个特别重要的因素，例如高热量膳食补充剂和地中海饮食以支持体重增加。本文的核心目的是调查痴呆和虚弱管理的趋势，重点是改善诊断和治疗。大量证据表明，均衡的营养和良好的身体活动是治疗的一个组成部分。值得注意的是，需要更多的循证医学知识。

关键词: 痴呆、虚弱、营养不良、中风、诊断、地中海饮食。

« Previous Next »
[1]
Robertson, D.A.; Savva, G.M.; Kenny, R.A. Frailty and cognitive impairment--a review of the evidence and causal mechanisms. Ageing Res. Rev., 2013, 12(4), 840-851.
[http://dx.doi.org/10.1016/j.arr.2013.06.004] [PMID: 23831959]
[2]
Schumacher, J.; Taylor, J-P.; Hamilton, C.A.; Firbank, M.; Donaghy, P.C.; Roberts, G.; Allan, L.; Durcan, R.; Barnett, N.; O’Brien, J.T.; Thomas, A.J. Functional connectivity in mild cognitive impairment with Lewy bodies. J. Neurol., 2021, 268(12), 4707-4720.
[http://dx.doi.org/10.1007/s00415-021-10580-z] [PMID: 33928432]
[3]
McKeith, I.G.; Boeve, B.F.; Dickson, D.W. Diagnosis and management of dementia with Lewy bodies. Neurology 2017, 89(1), 88-100.
[http://dx.doi.org/10.1212/WNL.0000000000004058]
[4]
McKeith, I.G.; Ferman, T.J.; Thomas, A.J.; Blanc, F.; Boeve, B.F.; Fujishiro, H.; Kantarci, K.; Muscio, C.; O’Brien, J.T.; Postuma, R.B.; Aarsland, D.; Ballard, C.; Bonanni, L.; Donaghy, P.; Emre, M.; Galvin, J.E.; Galasko, D.; Goldman, J.G.; Gomperts, S.N.; Honig, L.S.; Ikeda, M.; Leverenz, J.B.; Lewis, S.J.G.; Marder, K.S.; Masellis, M.; Salmon, D.P.; Taylor, J.P.; Tsuang, D.W.; Walker, Z.; Tiraboschi, P. Research criteria for the diagnosis of prodromal dementia with Lewy bodies. Neurology, 2020, 94(17), 743-755.
[http://dx.doi.org/10.1212/WNL.0000000000009323] [PMID: 32241955]
[5]
Brayne, C.; Gao, L.; Dewey, M.; Matthews, F.E. Dementia before death in ageing societies--the promise of prevention and the reality. PLoS Med., 2006, 3(10), e397.
[http://dx.doi.org/10.1371/journal.pmed.0030397] [PMID: 17076551]
[6]
Howard, R.; Gathercole, R.; Bradley, R.; Harper, E.; Davis, L.; Pank, L.; Lam, N.; Talbot, E.; Hooper, E.; Winson, R.; Scutt, B.; Ordonez Montano, V.; Nunn, S.; Lavelle, G.; Bateman, A.; Bentham, P.; Burns, A.; Dunk, B.; Forsyth, K.; Fox, C.; Poland, F.; Leroi, I.; Newman, S.; O’Brien, J.; Henderson, C.; Knapp, M.; Woolham, J.; Gray, R. The effectiveness and cost-effectiveness of assistive technology and telecare for independent living in dementia: A randomised controlled trial. Age Ageing, 2021, 50(3), 882-890.
[http://dx.doi.org/10.1093/ageing/afaa284] [PMID: 33492349]
[7]
Feter, N.; Leite, J.S.; Cardoso, R.K.; Rombaldi, A.J. Economic burden of physical inactivity in hospitalizations due to dementia: A Brazilian nationwide study. Cad. Saude Publica, 2021, 37(1), e00046520.
[http://dx.doi.org/10.1590/0102-311x00046520] [PMID: 33566988]
[8]
Petermann-Rocha, F.; Lyall, D.M.; Quinn, T.J.; Ho, F.K.; Pell, J.P.; Celis-Morales, C. Associations between physical frailty and dementia incidence: A prospective study from UK Biobank – Authors’ reply. Lancet Healthy Longev., 2021, 2(2), e68.
[http://dx.doi.org/10.1016/S2666-7568(21)00008-8]
[9]
Li, M.; Huang, Y.; Liu, Z.; Shen, R.; Chen, H.; Ma, C.; Zhang, T.; Li, S.; Prince, M. The association between frailty and incidence of dementia in Beijing: findings from 10/66 dementia research group population-based cohort study. BMC Geriatr., 2020, 20(1), 138.
[http://dx.doi.org/10.1186/s12877-020-01539-2] [PMID: 32293307]
[10]
Kawas, C.H.; Corrada, M.M. Alzheimer’s and dementia in the oldest-old: A century of challenges. Curr. Alzheimer Res., 2006, 3(5), 411-419.
[http://dx.doi.org/10.2174/156720506779025233] [PMID: 17168640]
[11]
Jellinger, K.A. The enigma of mixed dementia. Alzheimers Dement., 2007, 3(1), 40-53.
[http://dx.doi.org/10.1016/j.jalz.2006.09.002] [PMID: 19595916]
[12]
Rosa, G.; Giannotti, C.; Martella, L.; Massa, F.; Serafini, G.; Pardini, M.; Nobili, F.M.; Monacelli, F. Brain aging, cardiovascular diseases, mixed dementia, and frailty in the oldest old: From brain phenotype to clinical expression. J. Alzheimers Dis., 2020, 75(4), 1083-1103.
[http://dx.doi.org/10.3233/JAD-191075] [PMID: 32390618]
[13]
Kawas, C.H.; Kim, R.C.; Sonnen, J.A.; Bullain, S.S.; Trieu, T.; Corrada, M.M. Multiple pathologies are common and related to dementia in the oldest-old: The 90+ Study. Neurology, 2015, 85(6), 535-542.
[http://dx.doi.org/10.1212/WNL.0000000000001831] [PMID: 26180144]
[14]
Whitmer, R.A.; Sidney, S.; Selby, J.; Johnston, S.C.; Yaffe, K. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology, 2005, 64(2), 277-281.
[http://dx.doi.org/10.1212/01.WNL.0000149519.47454.F2] [PMID: 15668425]
[15]
de Bruijn, R.F.A.G.; Ikram, M.A. Cardiovascular risk factors and future risk of Alzheimer’s disease. BMC Med., 2014, 12(1), 130.
[http://dx.doi.org/10.1186/s12916-014-0130-5] [PMID: 25385322]
[16]
Attems, J.; Jellinger, K.A. The overlap between vascular disease and Alzheimer’s disease--lessons from pathology. BMC Med., 2014, 12(1), 206.
[http://dx.doi.org/10.1186/s12916-014-0206-2] [PMID: 25385447]
[17]
Rockwood, K.; Song, X.; MacKnight, C.; Bergman, H.; Hogan, D.B.; McDowell, I.; Mitnitski, A. A global clinical measure of fitness and frailty in elderly people. CMAJ, 2005, 173(5), 489-495.
[http://dx.doi.org/10.1503/cmaj.050051] [PMID: 16129869]
[18]
Morley, J.E.; Vellas, B.; van Kan, G.A.; Anker, S.D.; Bauer, J.M.; Bernabei, R.; Cesari, M.; Chumlea, W.C.; Doehner, W.; Evans, J.; Fried, L.P.; Guralnik, J.M.; Katz, P.R.; Malmstrom, T.K.; McCarter, R.J.; Gutierrez Robledo, L.M.; Rockwood, K.; von Haehling, S.; Vandewoude, M.F.; Walston, J. Frailty consensus: A call to action. J. Am. Med. Dir. Assoc., 2013, 14(6), 392-397.
[http://dx.doi.org/10.1016/j.jamda.2013.03.022] [PMID: 23764209]
[19]
Hoogendijk, E.O.; Afilalo, J.; Ensrud, K.E.; Kowal, P.; Onder, G.; Fried, L.P. Frailty: Implications for clinical practice and public health. 2019. Available from: www.thelancet.com
[20]
Delrieu, J.; Andrieu, S.; Pahor, M.; Cantet, C.; Cesari, M.; Ousset, P.J.; Voisin, T.; Fougère, B.; Gillette, S.; Carrie, I.; Vellas, B. Neuropsychological profile of “Cognitive Frailty” subjects in MAPT study. J. Prev. Alzheimers Dis., 2016, 3(3), 151-159.
[http://dx.doi.org/10.14283/jpad.2016.94] [PMID: 27547746]
[21]
Roppolo, M.; Mulasso, A.; Rabaglietti, E. Cognitive frailty in Italian community-dwelling older adults: Prevalence rate and its association with disability. J. Nutr. Health Aging, 2017, 21(6), 631-636.
[http://dx.doi.org/10.1007/s12603-016-0828-5] [PMID: 28537326]
[22]
Shimada, H.; Makizako, H.; Lee, S.; Doi, T.; Lee, S.; Tsutsumimoto, K.; Harada, K.; Hotta, R.; Bae, S.; Nakakubo, S.; Harada, K.; Suzuki, T. Impact of cognitive frailty on daily activities in older persons. J. Nutr. Health Aging, 2016, 20(7), 729-735.
[http://dx.doi.org/10.1007/s12603-016-0685-2] [PMID: 27499306]
[23]
Rohrmann, S. Epidemiology of frailty in older people. Adv. Exp. Med. Biol., 2020, 1216, 21-27.
[http://dx.doi.org/10.1007/978-3-030-33330-0_3] [PMID: 31894543]
[24]
Panza, F.; Lozupone, M.; Solfrizzi, V.; Sardone, R.; Dibello, V.; Di Lena, L.; D’Urso, F.; Stallone, R.; Petruzzi, M.; Giannelli, G.; Quaranta, N.; Bellomo, A.; Greco, A.; Daniele, A.; Seripa, D.; Logroscino, G. Different cognitive frailty models and health-and cognitive-related outcomes in older age: From epidemiology to prevention. J. Alzheimers Dis., 2018, 62(3), 993-1012.
[http://dx.doi.org/10.3233/JAD-170963] [PMID: 29562543]
[25]
Clissett, P.; Porock, D.; Harwood, R.H.; Gladman, J.R. The challenges of achieving person-centred care in acute hospitals: A qualitative study of people with dementia and their families. Int. J. Nurs. Stud., 2013, 50(11), 1495-1503.
[http://dx.doi.org/10.1016/j.ijnurstu.2013.03.001] [PMID: 23548170]
[26]
Oliver, D.; Burns, E. Geriatric medicine and geriatricians in the UK. How they relate to acute and general internal medicine and what the future might hold? Future Hosp. J., 2016, 3(1), 49-54.
[http://dx.doi.org/10.7861/futurehosp.3-1-49] [PMID: 31098179]
[27]
Hirt, J.; Beer, T. Use and impact of virtual reality simulation in dementia care education: A scoping review. Nurse Educ Today Churchill Livingstone, 2020, 84, 104207.
[http://dx.doi.org/10.1016/j.nedt.2019.104207] [PMID: 31669968]
[28]
Lai, C.; Cipriani, M.; Renzi, A.; Luciani, M.; Lombardo, L.; Aceto, P. The effects of the perception of being recognized by patients with alzheimer disease on a caregiver’s burden and psychophysical health. Am. J. Hosp. Palliat. Care, 2018, 35(9), 1188-1194.
[http://dx.doi.org/10.1177/1049909118766316] [PMID: 29580073]
[29]
Parra, M.A.; Butler, S.; McGeown, W.J.; Brown Nicholls, L.A.; Robertson, D.J. Globalising strategies to meet global challenges: the case of ageing and dementia. J. Glob. Health, 2019, 9(2), 020310.
[http://dx.doi.org/10.7189/jogh.09.020310] [PMID: 31777656]
[30]
Kojima, G.; Liljas, A.E.M.; Iliffe, S. Frailty syndrome: implications and challenges for health care policy. Risk Manag. Healthc. Policy, 2019, 12, 23-30.
[http://dx.doi.org/10.2147/RMHP.S168750] [PMID: 30858741]
[31]
Turner, G.; Clegg, A. Best practice guidelines for the management of frailty: A British Geriatrics Society, Age UK and Royal College of General Practitioners report. Age Ageing, 2014, 43(6), 744-747.
[http://dx.doi.org/10.1093/ageing/afu138] [PMID: 25336440]
[32]
Drennan, V.; Walters, K.; Avgerinou, C.; Gardner, B.; Goodman, C.; Frost, R.; Kharicha, K.; Iliffe, S.; Manthorpe, J. Moving upstream in health promoting policies for older people with early frailty in England? A policy analysis. J. Health Serv. Res. Policy, 2018, 23(3), 168-175.
[http://dx.doi.org/10.1177/1355819617752971] [PMID: 29325443]
[33]
Dent, E.; Martin, F.C.; Bergman, H.; Woo, J.; Romero-Ortuno, R.; Walston, J.D. Management of frailty: opportunities, challenges, and future directions. Lancet, 2019, 394(10206), 1376-1386.
[http://dx.doi.org/10.1016/S0140-6736(19)31785-4] [PMID: 31609229]
[34]
Sloane, P.D.; Cesari, M. Research on frailty: Continued progress, continued challenges. J. Am. Med. Dir. Assoc., 2018, 19(4), 279-281.
[http://dx.doi.org/10.1016/j.jamda.2018.01.003] [PMID: 29526597]
[35]
Achterberg, W.P.; Pieper, M.J.; van Dalen-Kok, A.H.; de Waal, M.W.; Husebo, B.S.; Lautenbacher, S.; Kunz, M.; Scherder, E.J.; Corbett, A. Pain management in patients with dementia. Clin. Interv. Aging, 2013, 8, 1471-1482.
[http://dx.doi.org/10.2147/CIA.S36739] [PMID: 24204133]
[36]
Walston, J. Frailty research moves beyond risk assessment. J. Gerontol. Ser. A, 2017, 72(7), 915-916.
[http://dx.doi.org/10.1093/gerona/glx085] [PMID: 28575291]
[37]
Bendayan, M.; Bibas, L.; Levi, M.; Mullie, L.; Forman, D.E.; Afilalo, J. Therapeutic interventions for frail elderly patients: part II. Ongoing and unpublished randomized trials. Prog. Cardiovasc. Dis. W.B., 2014, 57(2), 144-151.
[http://dx.doi.org/10.1016/j.pcad.2014.07.005] [PMID: 25216613]
[38]
Bibas, L.; Levi, M.; Bendayan, M.; Mullie, L.; Forman, D.E.; Afilalo, J. Therapeutic interventions for frail elderly patients: part I. Published randomized trials. Prog. Cardiovasc. Dis., 2014, 57(2), 134-143.
[http://dx.doi.org/10.1016/j.pcad.2014.07.004] [PMID: 25216612]
[39]
Cadore, E.L.; Rodríguez-Mañas, L.; Sinclair, A.; Izquierdo, M. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: A systematic review. Rejuvenation Res., 2013, 16(2), 105-114.
[http://dx.doi.org/10.1089/rej.2012.1397] [PMID: 23327448]
[40]
de Labra, C.; Guimaraes-Pinheiro, C.; Maseda, A.; Lorenzo, T.; Millán-Calenti, J.C. Effects of physical exercise interventions in frail older adults: A systematic review of randomized controlled trials. BMC Geriatr., 2015, 15(1), 154.
[http://dx.doi.org/10.1186/s12877-015-0155-4] [PMID: 26626157]
[41]
Dent, E.; Lien, C.; Lim, W.S.; Wong, W.C.; Wong, C.H.; Ng, T.P.; Woo, J.; Dong, B.; de la Vega, S.; Hua Poi, P.J.; Kamaruzzaman, S.B.B.; Won, C.; Chen, L.K.; Rockwood, K.; Arai, H.; Rodriguez-Mañas, L.; Cao, L.; Cesari, M.; Chan, P.; Leung, E.; Landi, F.; Fried, L.P.; Morley, J.E.; Vellas, B.; Flicker, L. The Asia-Pacific clinical practice guidelines for the management of frailty. J. Am. Med. Dir. Assoc., 2017, 18(7), 564-575.
[http://dx.doi.org/10.1016/j.jamda.2017.04.018] [PMID: 28648901]
[42]
Ng, T.P.; Feng, L.; Nyunt, M.S.Z.; Feng, L.; Niti, M.; Tan, B.Y.; Chan, G.; Khoo, S.A.; Chan, S.M.; Yap, P.; Yap, K.B. Nutritional, physical, cognitive, and combination interventions and frailty reversal among older adults: A randomized controlled trial. Am. J. Med., 2015, 128(11), 1225-1236.e1.
[http://dx.doi.org/10.1016/j.amjmed.2015.06.017] [PMID: 26159634]
[43]
Copeland, M.P.; Daly, E.; Hines, V.; Mastromauro, C.; Zaitchik, D.; Gunther, J.; Albert, M. Psychiatric symptomatology and prodromal Alzheimer’s disease. Alzheimer Dis. Assoc. Disord., 2003, 17(1), 1-8.
[http://dx.doi.org/10.1097/00002093-200301000-00001] [PMID: 12621314]
[44]
Geerlings, M.I.; Schmand, B.; Braam, A.W.; Jonker, C.; Bouter, L.M.; van Tilburg, W. Depressive symptoms and risk of Alzheimer’s disease in more highly educated older people. J. Am. Geriatr. Soc., 2000, 48(9), 1092-1097.
[http://dx.doi.org/10.1111/j.1532-5415.2000.tb04785.x] [PMID: 10983909]
[45]
Wimo, A.; Winblad, B.; Jönsson, L. An estimate of the total worldwide societal costs of dementia in 2005. Alzheimers Dement., 2007, 3(2), 81-91.
[http://dx.doi.org/10.1016/j.jalz.2007.02.001] [PMID: 19595921]
[46]
Lyketsos, C.G.; Lopez, O.; Jones, B.; Fitzpatrick, A.L.; Breitner, J.; DeKosky, S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA, 2002, 288(12), 1475-1483.
[http://dx.doi.org/10.1001/jama.288.12.1475] [PMID: 12243634]
[47]
Lopez, O.L. Mild cognitive impairment. Continuum. (Minneap Minn)., 2013, 19(2 Dementia), 411.
[http://dx.doi.org/10.1212/01.CON.0000429175.29601.97]
[48]
Fisicaro, F.; Lanza, G.; Pennisi, M.; Vagli, C.; Cantone, M.; Pennisi, G.; Ferri, R.; Bella, R. Moderate mocha coffee consumption is associated with higher cognitive and mood status in a non-demented elderly population with subcortical ischemic vascular disease. Nutrients, 2021, 13(2), 536.
[http://dx.doi.org/10.3390/nu13020536] [PMID: 33562065]
[49]
Harasani, K.; Xhafaj, D.; Lekaj, A.; Veshi, L.; Olvera-Porcel, M.D.C. Screening for mild cognitive impairment among older Albanian patients by clinical pharmacists. Int. J. Pharm. Pract., 2021, 29(2), 189-191.
[http://dx.doi.org/10.1093/ijpp/riab001] [PMID: 33729534]
[50]
Pandhita S, G.; Sutrisna, B.; Wibowo, S.; Adisasmita, A.C.; Rahardjo, T.B.W.; Amir, N.; Rustika, R.; Kosen, S.; Syarif, S.; Wreksoatmodjo, B.R. Decision tree clinical algorithm for screening of mild cognitive impairment in the elderly in primary health care: Development, test of accuracy, and time-effectiveness analysis. Neuroepidemiology, 2020, 54(3), 243-250.
[http://dx.doi.org/10.1159/000503830] [PMID: 32241012]
[51]
Bouchard, R.W. Diagnostic criteria of dementia. Can. J. Neurol. Sci., 2007. Available from: https://www.dementia.org.au/information/for-health-professionals/clinical-resources/diagnostic-criteria-for-dementia
[http://dx.doi.org/10.1017/S0317167100005497]
[52]
Larson, E.B.; Wang, L.; Bowen, J.D.; McCormick, W.C.; Teri, L.; Crane, P.; Kukull, W. Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Ann. Intern. Med., 2006, 144(2), 73-81.
[http://dx.doi.org/10.7326/0003-4819-144-2-200601170-00004] [PMID: 16418406]
[53]
Bongue, B.; Buisson, A.; Dupre, C.; Beland, F.; Gonthier, R.; Crawford-Achour, É. Predictive performance of four frailty screening tools in community-dwelling elderly. BMC Geriatr., 2017, 17(1), 262.
[http://dx.doi.org/10.1186/s12877-017-0633-y] [PMID: 29126383]
[54]
Bandeen-Roche, K.; Xue, Q-L.; Ferrucci, L.; Walston, J.; Guralnik, J.M.; Chaves, P.; Zeger, S.L.; Fried, L.P. Phenotype of frailty: characterization in the women’s health and aging studies. J. Gerontol. A Biol. Sci. Med. Sci., 2006, 61(3), 262-266.
[http://dx.doi.org/10.1093/gerona/61.3.262] [PMID: 16567375]
[55]
Rockwood, K.; Mitnitski, A. Frailty in relation to the accumulation of deficits. J. Gerontol. A Biol. Sci. Med. Sci., 2007, 62(7), 722-727.
[http://dx.doi.org/10.1093/gerona/62.7.722] [PMID: 17634318]
[56]
Creavin, S.T.; Wisniewski, S.; Noel-Storr, A.H.; Trevelyan, C.M.; Hampton, T.; Rayment, D.; Thom, V.M.; Nash, K.J.; Elhamoui, H.; Milligan, R.; Patel, A.S.; Tsivos, D.V.; Wing, T.; Phillips, E.; Kellman, S.M.; Shackleton, H.L.; Singleton, G.F.; Neale, B.E.; Watton, M.E.; Cullum, S. Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations. Cochrane Database Syst. Rev., 2016, (1), CD011145.
[http://dx.doi.org/10.1002/14651858.CD011145.pub2] [PMID: 26760674]
[57]
Mathuranath, P.S.; Cherian, J.P.; Mathew, R.; George, A.; Alexander, A.; Sarma, S.P. Mini mental state examination and the Addenbrooke’s cognitive examination: effect of education and norms for a multicultural population. Neurol. India, 2007, 55(2), 106-110.
[http://dx.doi.org/10.4103/0028-3886.32779] [PMID: 17558112]
[58]
Kim, Y.; Jang, S.N. Mapping the knowledge structure of frailty in journal articles by text network analysis. PLoS One, 2018, 13(4), e0196104.
[http://dx.doi.org/10.1371/journal.pone.0196104] [PMID: 29672647]
[59]
Han, C.; Jo, S.A.; Jo, I.; Kim, E.; Park, M.H.; Kang, Y. An adaptation of the Korean mini-mental state examination (K-MMSE) in elderly Koreans: demographic influence and population-based norms (the AGE study). Arch. Gerontol. Geriatr., 2008, 47(3), 302-310.
[http://dx.doi.org/10.1016/j.archger.2007.08.012] [PMID: 17936377]
[60]
Smith, T.; Gildeh, N.; Holmes, C. The Montreal Cognitive Assessment: validity and utility in a memory clinic setting. Can. J. Psychiatry, 2007, 52(5), 329-332.
[http://dx.doi.org/10.1177/070674370705200508] [PMID: 17542384]
[61]
Nasreddine, Z.S.; Phillips, N.A.; Bédirian, V.; Charbonneau, S.; Whitehead, V.; Collin, I.; Cummings, J.L.; Chertkow, H. The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment. J. Am. Geriatr. Soc., 2005, 53(4), 695-699.
[http://dx.doi.org/10.1111/j.1532-5415.2005.53221.x] [PMID: 15817019]
[62]
Yeo, T.Y.; Kim, K.; Park, M.H. Conversion from the Korean dementia screening questionnaire to the informant questionnaire on cognitive decline in the elderly. Neuropsychiatr. Dis. Treat., 2019, 15, 3205-3211.
[http://dx.doi.org/10.2147/NDT.S229555] [PMID: 31819448]
[63]
Lee, S.J.; Han, J.H.; Hwang, J.W.; Paik, J.W.; Han, C.; Park, M.H. Screening for normal cognition, mild cognitive impairment, and dementia with the Korean dementia screening questionnaire. Psychiatry Investig., 2018, 15(4), 384-389.
[http://dx.doi.org/10.30773/pi.2017.08.24] [PMID: 29475235]
[64]
Hoops, S.; Nazem, S.; Siderowf, A.D.; Duda, J.E.; Xie, S.X.; Stern, M.B.; Weintraub, D. Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease. Neurology, 2009, 73(21), 1738-1745.
[http://dx.doi.org/10.1212/WNL.0b013e3181c34b47] [PMID: 19933974]
[65]
Freitas, S.; Simões, M.R.; Alves, L.; Duro, D.; Santana, I. Montreal Cognitive Assessment (MoCA): validation study for frontotemporal dementia. J. Geriatr. Psychiatry Neurol., 2012, 25(3), 146-154.
[http://dx.doi.org/10.1177/0891988712455235] [PMID: 22859702]
[66]
Peters, L.L.; Boter, H.; Buskens, E.; Slaets, J.P. Measurement properties of the Groningen Frailty Indicator in home-dwelling and institutionalized elderly people. J. Am. Med. Dir. Assoc., 2012, 13(6), 546-551.
[http://dx.doi.org/10.1016/j.jamda.2012.04.007] [PMID: 22579590]
[67]
Arvanitakis, Z.; Shah, R.C.; Bennett, D.A. Diagnosis and management of dementia. JAMA, 2019, 322(16), 1589-1599.
[http://dx.doi.org/10.1001/jama.2019.4782] [PMID: 31638686]
[68]
Salardini, A. An overview of primary dementias as clinicopathological entities. Semin, 2019, 39(2), 153-166.
[http://dx.doi.org/10.1055/s-0039-1683445] [PMID: 30925609]
[69]
Panhwar, Y.N.; Naghdy, F.; Naghdy, G.; Stirling, D.; Potter, J. Assessment of frailty: A survey of quantitative and clinical methods. BMC Biomed. Eng., 2019, 1(1), 7.
[http://dx.doi.org/10.1186/s42490-019-0007-y] [PMID: 32903310]
[70]
Solfrizzi, V.; Scafato, E.; Frisardi, V.; Seripa, D.; Logroscino, G.; Maggi, S.; Imbimbo, B.P.; Galluzzo, L.; Baldereschi, M.; Gandin, C.; Di Carlo, A.; Inzitari, D.; Crepaldi, G.; Pilotto, A.; Panza, F. Frailty syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Aging. Alzheimers Dement., 2013, 9(2), 113-122.
[http://dx.doi.org/10.1016/j.jalz.2011.09.223] [PMID: 23245560]
[71]
Borda, M.G.; Soennesyn, H.; Steves, C.J.; Osland Vik-Mo, A.; Pérez-Zepeda, M.U.; Aarsland, D. Frailty in older adults with mild dementia: Dementia with Lewy bodies and Alzheimer’s disease. Dement. Geriatr. Cogn. Disord. Extra, 2019, 9(1), 176-183.
[http://dx.doi.org/10.1159/000496537]
[72]
Feldman, H.H.; Jacova, C.; Robillard, A.; Garcia, A.; Chow, T.; Borrie, M.; Schipper, H.M.; Blair, M.; Kertesz, A.; Chertkow, H. Diagnosis and treatment of dementia: 2. Diagnosis. CMAJ, 2008, 178(7), 825-836.
[http://dx.doi.org/10.1503/cmaj.070798] [PMID: 18362376]
[73]
Wang, D.C.; Black, S.E.; Zukotynski, K.A. Diagnosing dementia. CMAJ, 2016, 188(8), 603.
[http://dx.doi.org/10.1503/cmaj.150508] [PMID: 27067820]
[74]
Woolford, S.J.; Sohan, O.; Dennison, E.M.; Cooper, C.; Patel, H.P. Approaches to the diagnosis and prevention of frailty. Aging Clin. Exp. Res., 2020, 32(9), 1629-1637.
[http://dx.doi.org/10.1007/s40520-020-01559-3] [PMID: 32356135]
[75]
Evertson, L.C.; Jennings, L.A.; Reuben, D.B.; Zaila, K.E.; Akram, N.; Romero, T.; Tan, Z.S. Caregiver outcomes of a dementia care program. Geriatr. Nurs., 2021, 42(2), 447-459.
[http://dx.doi.org/10.1016/j.gerinurse.2021.02.003] [PMID: 33714024]
[76]
Allegri, R.F.; Glaser, F.B.; Taragano, F.E.; Buschke, H. Mild cognitive impairment: believe it or not? Int. Rev. Psychiatry, 2008, 20(4), 357-363.
[http://dx.doi.org/10.1080/09540260802095099] [PMID: 18925484]
[77]
Kulmala, J.; Nykänen, I.; Mänty, M.; Hartikainen, S. Association between frailty and dementia: A population-based study. Gerontology, 2014, 60(1), 16-21.
[http://dx.doi.org/10.1159/000353859] [PMID: 23970189]
[78]
Falk, N.; Cole, A.; Meredith, T.J. Evaluation of suspected dementia. Am. Fam. Physician, 2018, 97(6), 398-405.
[PMID: 29671539]
[79]
Aminzadeh, F.; Molnar, F.J.; Dalziel, W.B.; Ayotte, D. A review of barriers and enablers to diagnosis and management of persons with dementia in primary care. Can. Geriatr. J., 2012, 15(3), 85-94.
[http://dx.doi.org/10.5770/cgj.15.42] [PMID: 23259021]
[80]
Naylor, M.D.; Kurtzman, E.T. The role of nurse practitioners in reinventing primary care. Health Aff. (Millwood), 2010, 29(5), 893-899.
[http://dx.doi.org/10.1377/hlthaff.2010.0440] [PMID: 20439877]
[81]
Banerjee, D.; Vajawat, B.; Varshney, P.; Rao, T.S. Perceptions, experiences, and challenges of physicians involved in dementia care during the COVID-19 lockdown in India: A qualitative study. Front. Psychiatry, 2021, 11, 615758.
[http://dx.doi.org/10.3389/fpsyt.2020.615758] [PMID: 33551877]
[82]
Rantala, M.; Kankkunen, P.; Kvist, T.; Hartikainen, S. Barriers to postoperative pain management in hip fracture patients with dementia as evaluated by nursing staff. Pain Manag. Nurs., 2014, 15(1), 208-219.
[http://dx.doi.org/10.1016/j.pmn.2012.08.007] [PMID: 24602437]
[83]
Teel, C.S. Rural practitioners’ experiences in dementia diagnosis and treatment. Aging Ment. Health, 2004, 8(5), 422-429.
[http://dx.doi.org/10.1080/13607860410001725018] [PMID: 15511740]
[84]
Brayne, C.; Fox, C.; Boustani, M. Dementia screening in primary care: is it time? JAMA, 2007, 298(20), 2409-2411.
[http://dx.doi.org/10.1001/jama.298.20.2409] [PMID: 18042918]
[85]
Buhagiar, K.; Afzal, N.; Cosgrave, M. Behavioural and psychological symptoms of dementia in primary care: A survey of general practitioners in Ireland. Ment. Health Fam. Med., 2011, 8(4), 227-234.
[PMID: 23205063]
[86]
Fowler, N.R.; Perkins, A.J.; Gao, S. Risks and benefits of screening for dementia in primary care: The IU CHOICE trial. J. Am. Geriatr. Soc., 2020, 68(3), 535.
[http://dx.doi.org/10.1111/jgs.16247] [PMID: 31792940]
[87]
Ellis, G.; Gardner, M.; Tsiachristas, A.; Langhorne, P.; Burke, O.; Harwood, R.H.; Conroy, S.P.; Kircher, T.; Somme, D.; Saltvedt, I.; Wald, H.; O’Neill, D.; Robinson, D.; Shepperd, S. Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst. Rev., 2017, 9(9), CD006211.
[http://dx.doi.org/10.1002/14651858.CD006211.pub3] [PMID: 28898390]
[88]
Bradford, A.; Kunik, M.E.; Schulz, P.; Williams, S.P.; Singh, H. Missed and delayed diagnosis of dementia in primary care: prevalence and contributing factors. Alzheimer Dis. Assoc. Disord., 2009, 23(4), 306-314.
[http://dx.doi.org/10.1097/WAD.0b013e3181a6bebc] [PMID: 19568149]
[89]
Gandhi, T.K.; Kachalia, A.; Thomas, E.J.; Puopolo, A.L.; Yoon, C.; Brennan, T.A.; Studdert, D.M. Missed and delayed diagnoses in the ambulatory setting: A study of closed malpractice claims. Ann. Intern. Med., 2006, 145(7), 488-496.
[http://dx.doi.org/10.7326/0003-4819-145-7-200610030-00006] [PMID: 17015866]
[90]
Graber, M.L.; Franklin, N.; Gordon, R. Diagnostic error in internal medicine. Arch. Intern. Med., 2005, 165(13), 1493-1499.
[http://dx.doi.org/10.1001/archinte.165.13.1493] [PMID: 16009864]
[91]
Lambert, B.L.; Schiff, G.D.; Kim, S. Diagnosing diagnostic errors: Lessons from a multi-institutional collaborative. Agency for Healthcare Research and Quality (US); MD: Rockville, 2005.
[92]
Singh, H.; Petersen, L.A.; Thomas, E.J. Understanding diagnostic errors in medicine: A lesson from aviation. Qual. Saf. Health Care, 2006, 15(3), 159-164.
[http://dx.doi.org/10.1136/qshc.2005.016444] [PMID: 16751463]
[93]
Singh, H.; Naik, A.D.; Rao, R.; Petersen, L.A. Reducing diagnostic errors through effective communication: harnessing the power of information technology. J. Gen. Intern. Med., 2008, 23(4), 489-494.
[http://dx.doi.org/10.1007/s11606-007-0393-z] [PMID: 18373151]
[94]
Phung, T.K.T.; Waltoft, B.L.; Kessing, L.V.; Mortensen, P.B.; Waldemar, G. Time trend in diagnosing dementia in secondary care. Dement. Geriatr. Cogn. Disord., 2010, 29(2), 146-153.
[http://dx.doi.org/10.1159/000269933] [PMID: 20150733]
[95]
Panza, F.; Solfrizzi, V.; Frisardi, V.; Maggi, S.; Sancarlo, D.; Adante, F.; D’Onofrio, G.; Seripa, D.; Pilotto, A. Different models of frailty in predementia and dementia syndromes. J. Nutr. Health Aging, 2011, 15(8), 711-719.
[http://dx.doi.org/10.1007/s12603-011-0126-1] [PMID: 21968870]
[96]
Alagiakrishnan, K. Overcoming the barriers to the diagnosis of dementia. Postgrad. Med., 2010, 122(4), 105-111.
[http://dx.doi.org/10.3810/pgm.2010.07.2178] [PMID: 20675974]
[97]
Birch, D.; Draper, J. A critical literature review exploring the challenges of delivering effective palliative care to older people with dementia. J. Clin. Nurs., 2008, 17(9), 1144-1163.
[http://dx.doi.org/10.1111/j.1365-2702.2007.02220.x] [PMID: 18416791]
[98]
Sinclair, A.J.; Abdelhafiz, A.H.; Rodríguez-Mañas, L. Frailty and sarcopenia - newly emerging and high impact complications of diabetes. J. Diabetes Complications, 2017, 31(9), 1465-1473.
[http://dx.doi.org/10.1016/j.jdiacomp.2017.05.003] [PMID: 28669464]
[99]
Bruneau, B. Barriers to the management of pain in dementia care. Nurs. Times, 2014, 110(28), 12-, 14-16.
[PMID: 25087440]
[100]
Livingston, G.; Huntley, J.; Sommerlad, A.; Ames, D.; Ballard, C.; Banerjee, S.; Brayne, C.; Burns, A.; Cohen-Mansfield, J.; Cooper, C.; Costafreda, S.G.; Dias, A.; Fox, N.; Gitlin, L.N.; Howard, R.; Kales, H.C.; Kivimäki, M.; Larson, E.B.; Ogunniyi, A.; Orgeta, V.; Ritchie, K.; Rockwood, K.; Sampson, E.L.; Samus, Q.; Schneider, L.S.; Selbæk, G.; Teri, L.; Mukadam, N. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet, 2020, 396(10248), 413-446.
[http://dx.doi.org/10.1016/S0140-6736(20)30367-6] [PMID: 32738937]
[101]
Leyhe, T.; Reynolds, C.F., III; Melcher, T.; Linnemann, C.; Klöppel, S.; Blennow, K.; Zetterberg, H.; Dubois, B.; Lista, S.; Hampel, H. A common challenge in older adults: Classification, overlap, and therapy of depression and dementia. Alzheimers Dement., 2017, 13(1), 59-71.
[http://dx.doi.org/10.1016/j.jalz.2016.08.007] [PMID: 27693188]
[102]
van Swieten, J.C.; Heutink, P. Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia. Lancet Neurol., 2008, 7(10), 965-974.
[http://dx.doi.org/10.1016/S1474-4422(08)70194-7] [PMID: 18771956]
[103]
Cenik, B.; Sephton, C.F.; Dewey, C.M.; Xian, X.; Wei, S.; Yu, K.; Niu, W.; Coppola, G.; Coughlin, S.E.; Lee, S.E.; Dries, D.R.; Almeida, S.; Geschwind, D.H.; Gao, F.B.; Miller, B.L.; Farese, R.V., Jr; Posner, B.A.; Yu, G.; Herz, J. Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. J. Biol. Chem., 2011, 286(18), 16101-16108.
[http://dx.doi.org/10.1074/jbc.M110.193433] [PMID: 21454553]
[104]
Almeida, S.; Gao, F.; Coppola, G.; Gao, F.B. Suberoylanilide hydroxamic acid increases progranulin production in iPSC-derived cortical neurons of frontotemporal dementia patients. Neurobiol. Aging, 2016, 42, 35-40.
[http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.001] [PMID: 27143419]
[105]
Arrant, A.E.; Onyilo, V.C.; Unger, D.E.; Roberson, E.D. Neurobiology of disease progranulin gene therapy improves lysosomal dysfunction and microglial pathology associated with frontotemporal dementia and neuronal ceroid lipofuscinosis. J. Neurosci., 2018, 38(9), 2341-2358.
[http://dx.doi.org/10.1523/JNEUROSCI.3081-17.2018] [PMID: 29378861]
[106]
Loprinzi, P.D.; Frith, E.; Edwards, M.K.; Sng, E.; Ashpole, N. The effects of exercise on memory function among young to middle-aged adults: Systematic review and recommendations for future research. Am. J. Health Promot., 2018, 32(3), 691-704.
[http://dx.doi.org/10.1177/0890117117737409] [PMID: 29108442]
[107]
Krell-Roesch, J.; Feder, N.T.; Roberts, R.O.; Mielke, M.M.; Christianson, T.J.; Knopman, D.S.; Petersen, R.C.; Geda, Y.E. Leisure-time physical activity and the risk of incident dementia: The Mayo Clinic Study of Aging. J. Alzheimers Dis., 2018, 63(1), 149-155.
[http://dx.doi.org/10.3233/JAD-171141] [PMID: 29614667]
[108]
Arsenault-Lapierre, G.; Sourial, N.; Pakzad, S.; Hardouin, M.; Couturier, Y.; Bergman, H.; Vedel, I. Validation of a questionnaire for family physicians: Knowledge, attitude, practice on dementia care. Can. J. Aging, 2021, 40(2), 238-247.
[http://dx.doi.org/10.1017/S0714980820000069] [PMID: 32366352]
[109]
Scuteri, D.; Rombolà, L.; Morrone, L.A.; Bagetta, G.; Sakurada, S.; Sakurada, T.; Tonin, P.; Corasaniti, M.T. Neuropharmacology of the neuropsychiatric symptoms of dementia and role of pain: Essential oil of bergamot as a novel therapeutic approach. Int. J. Mol. Sci., 2019, 20(13), 3327.
[http://dx.doi.org/10.3390/ijms20133327] [PMID: 31284573]
[110]
Ralph, S.J.; Espinet, A.J. Use of antipsychotics and benzodiazepines for dementia: Time for action? What will be required before global de-prescribing? Dementia, 2019, 18(6), 2322-2339.
[http://dx.doi.org/10.1177/1471301217746769] [PMID: 29271252]
[111]
Scuteri, D.; Cassano, R.; Trombino, S.; Russo, R.; Mizoguchi, H.; Watanabe, C.; Hamamura, K.; Katsuyama, S.; Komatsu, T.; Morrone, L.A.; Rombolà, L.; Adornetto, A.; Laganà, A.S.; Corasaniti, M.T.; Tonin, P.; Sakurada, S.; Sakurada, T.; Nicotera, P.; Bagetta, G. Development and translation of NanoBEO, a nanotechnology-based delivery system of bergamot essential oil deprived of furocumarins, in the control of agitation in severe dementia. Pharmaceutics, 2021, 13(3), 379.
[http://dx.doi.org/10.3390/pharmaceutics13030379] [PMID: 33809385]
[112]
Goldstein-Levitas, N. Dance/movement therapy and sensory stimulation: A holistic approach to dementia care. Am. J. Dance Ther., 2016, 38(2), 429-436.
[http://dx.doi.org/10.1007/s10465-016-9221-5]
[113]
Karkou, V.; Meekums, B. Dance movement therapy for dementia. Cochrane Database Syst. Rev., 2017, 2, CD011022.
[PMID: 28155990]
[114]
Ho, R.T.H.; Fong, T.C.T.; Chan, W.C.; Kwan, J.S.K.; Chiu, P.K.C.; Yau, J.C.Y.; Lam, L.C.W. Psychophysiological effects of dance movement therapy and physical exercise on older adults with mild dementia: A randomized controlled trial. J. Gerontol. B Psychol. Sci. Soc. Sci., 2020, 75(3), 560-570.
[PMID: 30496547]
[115]
Mitchell, S.L.; Black, B.S.; Ersek, M.; Hanson, L.C.; Miller, S.C.; Sachs, G.A.; Teno, J.M.; Morrison, R.S. Advanced dementia: state of the art and priorities for the next decade. Ann. Intern. Med., 2012, 156(1 Pt 1), 45-51.
[http://dx.doi.org/10.7326/0003-4819-156-1-201201030-00008] [PMID: 22213494]
[116]
Savica, R.; Petersen, R.C. Prevention of dementia. Psychiatr. Clin. North Am., 2011, 34(1), 127-145.
[http://dx.doi.org/10.1016/j.psc.2010.11.006] [PMID: 21333844]
[117]
Dishman, R.K.; O’Connor, P.J. Lessons in exercise neurobiology: The case of endorphins. Ment. Health Phys. Act., 2009, 2(1), 4-9.
[http://dx.doi.org/10.1016/j.mhpa.2009.01.002]
[118]
Gagliardi, S.; Morasso, C.; Stivaktakis, P.; Pandini, C.; Tinelli, V.; Tsatsakis, A.; Prosperi, D.; Hickey, M.; Corsi, F.; Cereda, C. Curcumin formulations and trials: What’s new in neurological diseases. Molecules, 2020, 25(22), 5389.
[http://dx.doi.org/10.3390/molecules25225389] [PMID: 33217959]
[119]
Ninomiya, T. Diabetes mellitus and dementia. Curr. Diab. Rep., 2014, 14(5), 487.
[http://dx.doi.org/10.1007/s11892-014-0487-z] [PMID: 24623199]
[120]
Livingston, G.; Sommerlad, A.; Orgeta, V.; Costafreda, S.G.; Huntley, J.; Ames, D.; Ballard, C.; Banerjee, S.; Burns, A.; Cohen-Mansfield, J.; Cooper, C.; Fox, N.; Gitlin, L.N.; Howard, R.; Kales, H.C.; Larson, E.B.; Ritchie, K.; Rockwood, K.; Sampson, E.L.; Samus, Q.; Schneider, L.S.; Selbæk, G.; Teri, L.; Mukadam, N. Dementia prevention, intervention, and care. Lancet, 2017, 390(10113), 2673-2734.
[http://dx.doi.org/10.1016/S0140-6736(17)31363-6] [PMID: 28735855]
[121]
Hersi, M.; Irvine, B.; Gupta, P.; Gomes, J.; Birkett, N.; Krewski, D. Risk factors associated with the onset and progression of Alzheimer’s disease: A systematic review of the evidence. Neurotoxicology, 2017, 61, 143-187.
[http://dx.doi.org/10.1016/j.neuro.2017.03.006] [PMID: 28363508]
[122]
Abbott, R.D.; White, L.R.; Ross, G.W.; Masaki, K.H.; Curb, J.D.; Petrovitch, H. Walking and dementia in physically capable elderly men. JAMA, 2004, 292(12), 1447-1453.
[http://dx.doi.org/10.1001/jama.292.12.1447] [PMID: 15383515]
[123]
Bartels, C.; Wagner, M.; Wolfsgruber, S.; Ehrenreich, H.; Schneider, A. Impact of SSRI therapy on risk of conversion from mild cognitive impairment to Alzheimer’s dementia in individuals with previous depression. Am. J. Psychiatry, 2018, 175(3), 232-241.
[http://dx.doi.org/10.1176/appi.ajp.2017.17040404] [PMID: 29179578]
[124]
Petersen, R.C.; Thomas, R.G.; Grundman, M.; Bennett, D.; Doody, R.; Ferris, S.; Galasko, D.; Jin, S.; Kaye, J.; Levey, A.; Pfeiffer, E.; Sano, M.; van Dyck, C.H.; Thal, L.J. Vitamin E and donepezil for the treatment of mild cognitive impairment. N. Engl. J. Med., 2005, 352(23), 2379-2388.
[http://dx.doi.org/10.1056/NEJMoa050151] [PMID: 15829527]
[125]
Alzheimer’s Disease International. The state of the art of dementia research. World Alzheimer Report 2018.
[126]
Bisiani, L.; Angus, J. Doll therapy: A therapeutic means to meet past attachment needs and diminish behaviours of concern in a person living with dementia--a case study approach. Dementia, 2013, 12(4), 447-462.
[http://dx.doi.org/10.1177/1471301211431362] [PMID: 24336954]
[127]
Zhang, Y.S.; Li, J.D.; Yan, C. An update on vinpocetine: New discoveries and clinical implications. Eur. J. Pharmacol., 2018, 819, 30-34.
[http://dx.doi.org/10.1016/j.ejphar.2017.11.041] [PMID: 29183836]
[128]
Tariot, P.N.; Farlow, M.R.; Grossberg, G.T.; Graham, S.M.; McDonald, S.; Gergel, I. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: A randomized controlled trial. JAMA, 2004, 291(3), 317-324.
[http://dx.doi.org/10.1001/jama.291.3.317] [PMID: 14734594]
[129]
Sommerlad, A.; Sabia, S.; Singh-Manoux, A.; Lewis, G.; Livingston, G. Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study. PLoS Med., 2019, 16(8), e1002862.
[http://dx.doi.org/10.1371/journal.pmed.1002862] [PMID: 31374073]
[130]
Kelly, M.E.; Duff, H.; Kelly, S.; McHugh Power, J.E.; Brennan, S.; Lawlor, B.A.; Loughrey, D.G. The impact of social activities, social networks, social support and social relationships on the cognitive functioning of healthy older adults: A systematic review. Syst. Rev., 2017, 6(1), 259.
[http://dx.doi.org/10.1186/s13643-017-0632-2] [PMID: 29258596]
[131]
Williams, J.W.; Plassman, B.L.; Burke, J.; Benjamin, S. Preventing Alzheimer’s disease and cognitive decline. Evid. Rep. Technol. Assess. (Full. Rep), 2010, (193), 1-727.
[PMID: 21500874]
[132]
Saito, T.; Murata, C.; Saito, M.; Takeda, T.; Kondo, K. Influence of social relationship domains and their combinations on incident dementia: A prospective cohort study. J. Epidemiol. Community Health, 2018, 72(1), 7-12.
[http://dx.doi.org/10.1136/jech-2017-209811] [PMID: 29089367]
[133]
Bhattacharya, T.; Soares, G.A.B.E.; Chopra, H.; Rahman, M.M.; Hasan, Z.; Swain, S.S.; Cavalu, S. Applications of phyto-nanotechnology for the treatment of neurodegenerative disorders. Materials (Basel), 2022, 15(3), 804.
[http://dx.doi.org/10.3390/ma15030804] [PMID: 35160749]
[134]
Rahman, M.M.; Islam, M.R.; Islam, M.T.; Harun-Or-Rashid, M.; Islam, M.; Abdullah, S.; Uddin, M.B.; Das, S.; Rahaman, M.S.; Ahmed, M.; Alhumaydhi, F.A.; Emran, T.B.; Mohamed, A.A.; Faruque, M.R.I.; Khandaker, M.U.; Mostafa-Hedeab, G. Stem cell transplantation therapy and neurological disorders: Current status and future perspectives. Biology (Basel), 2022, 11(1), 147.
[http://dx.doi.org/10.3390/biology11010147] [PMID: 35053145]
[135]
Rahman, M.M.; Ferdous, K.S.; Ahmed, M.; Islam, M.T.; Khan, M.R.; Perveen, A.; Ashraf, G.M.; Uddin, M.S. Hutchinson-Gilford Progeria Syndrome: An overview of the molecular mechanism, pathophysiology and therapeutic approach. Curr. Genet., 2021, 21(3), 216-229.
[http://dx.doi.org/10.2174/1566523221666210303100805] [PMID: 33655857]
[136]
Middleton, L.E.; Yaffe, K. Promising strategies for the prevention of dementia. Arch. Neurol., 2009, 66(10), 1210-1215.
[http://dx.doi.org/10.1001/archneurol.2009.201] [PMID: 19822776]
[137]
Koch, H.J.; Uyanik, G.; Fischer-Barnicol, D. Memantine: A therapeutic approach in treating Alzheimer’s and vascular dementia. Curr. Drug Targets CNS Neurol. Disord., 2005, 4(5), 499-506.
[http://dx.doi.org/10.2174/156800705774322021] [PMID: 16266284]
[138]
Tomas, C.; Newton, J.; Watson, S. A review of hypothalamic-pituitary-adrenal axis function in chronic fatigue syndrome. ISRN Neurosci., 2013, 2013, 784520.
[http://dx.doi.org/10.1155/2013/784520] [PMID: 24959566]
[139]
WHO. Risk reduction of cognitive decline and dementia who guidelines., 2019. Available from: https://www.who.int/publications/i/item/9789241550543
[140]
Schneider, J.A.; Arvanitakis, Z.; Bang, W.; Bennett, D.A. Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology, 2007, 69(24), 2197-2204.
[http://dx.doi.org/10.1212/01.wnl.0000271090.28148.24] [PMID: 17568013]
[141]
McMaster, M.; Kim, S.; Clare, L.; Torres, S.J.; Cherbuin, N.; DʼEste, C.; Anstey, K.J. Lifestyle risk factors and cognitive outcomes from the multidomain dementia risk reduction randomized controlled trial, Body Brain Life for Cognitive Decline (BBL-CD). J. Am. Geriatr. Soc., 2020, 68(11), 2629-2637.
[http://dx.doi.org/10.1111/jgs.16762] [PMID: 32909259]
[142]
McCleery, J.; Abraham, R.P.; Denton, D.A.; Rutjes, A.W.; Chong, L.Y.; Al-Assaf, A.S.; Griffith, D.J.; Rafeeq, S.; Yaman, H.; Malik, M.A.; Di Nisio, M.; Martínez, G.; Vernooij, R.W.; Tabet, N. Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment. Cochrane Database Syst. Rev., 2018, 11(2), CD011905.
[http://dx.doi.org/10.1002/14651858.CD011905.pub2] [PMID: 30383288]
[143]
Smith, A.D. Prevention of dementia: A role for B vitamins? Nutr. Health, 2006, 18(3), 225-226.
[http://dx.doi.org/10.1177/026010600601800304] [PMID: 17180867]
[144]
Rahman, M.M.; Rahaman, M.S.; Islam, M.R.; Rahman, F.; Mithi, F.M.; Alqahtani, T.; Almikhlafi, M.A.; Alghamdi, S.Q.; Alruwaili, A.S.; Hossain, M.S.; Ahmed, M.; Das, R.; Emran, T.B.; Uddin, M.S. Role of phenolic compounds in human disease: Current knowledge and future prospects. Molecules, 2021, 27(1), 233.
[http://dx.doi.org/10.3390/molecules27010233] [PMID: 35011465]
[145]
Clarke, R. Vitamin B12, folic acid, and the prevention of dementia. N. Engl. J. Med., 2006, 354(26), 2817-2819.
[http://dx.doi.org/10.1056/NEJMe068086] [PMID: 16807420]
[146]
Murphy, J.L.; Holmes, J.; Brooks, C. Nutrition and dementia care: developing an evidence-based model for nutritional care in nursing homes. BMC Geriatr., 2017, 17(1), 55.
[http://dx.doi.org/10.1186/s12877-017-0443-2] [PMID: 28196475]
[147]
Annweiler, C. Vitamin D in dementia prevention. Ann. N. Y. Acad. Sci., 2016, 1367(1), 57-63.
[http://dx.doi.org/10.1111/nyas.13058] [PMID: 27116242]
[148]
Annweiler, C.; Schott, A-M.; Berrut, G.; Chauviré, V.; Le Gall, D.; Inzitari, M.; Beauchet, O. Vitamin D and ageing: neurological issues. Neuropsychobiology, 2010, 62(3), 139-150.
[http://dx.doi.org/10.1159/000318570] [PMID: 20628264]
[149]
Cheng, S.T. Cognitive reserve and the prevention of dementia: The role of physical and cognitive activities. Curr. Psychiatry Rep., 2016, 18(9), 85.
[http://dx.doi.org/10.1007/s11920-016-0721-2] [PMID: 27481112]
[150]
Valenzuela, M.J. Brain reserve and the prevention of dementia. Curr. Opin. Psychiatry, 2008, 21(3), 296-302.
[http://dx.doi.org/10.1097/YCO.0b013e3282f97b1f] [PMID: 18382231]
[151]
Valenzuela, M.J.; Sachdev, P. Brain reserve and dementia: A systematic review. Psychol. Med., 2006, 36(4), 441-454.
[http://dx.doi.org/10.1017/S0033291705006264] [PMID: 16207391]
[152]
Guillem, F.; Mograss, M. Brain reserve and dementia: A systematic review. Psychol. Med., 2005.
[153]
Wang, J.Y.J.; Zhou, D.H.D.; Li, J.; Zhang, M.; Deng, J.; Tang, M.; Gao, C.; Li, J.; Lian, Y.; Chen, M. Leisure activity and risk of cognitive impairment: the Chongqing aging study. Neurology, 2006, 66(6), 911-913.
[http://dx.doi.org/10.1212/01.wnl.0000192165.99963.2a] [PMID: 16291928]
[154]
Drey, M.; Pfeifer, K.; Sieber, C.C. The fried frailty criteria as inclusion criteria for a randomized controlled trial: personal experience and literature review. Gerontology, 2011, 57, 11-18.
[http://dx.doi.org/10.1159/000313433]
[155]
Liau, S.J.; Lalic, S.; Sluggett, J.K.; Cesari, M.; Onder, G.; Vetrano, D.L.; Morin, L.; Hartikainen, S.; Hamina, A.; Johnell, K.; Tan, E.C.K.; Visvanathan, R.; Bell, J.S. Medication management in frail older people: Consensus principles for clinical practice, research, and education. J. Am. Med. Dir. Assoc., 2021, 22(1), 43-49.
[http://dx.doi.org/10.1016/j.jamda.2020.05.004] [PMID: 32669236]
[156]
Windhaber, T.; Koula, M.L.; Ntzani, E.; Velivasi, A.; Rizos, E.; Doumas, M.T.; Pappas, E.E.; Onder, G.; Vetrano, D.L.; Roudriguez Laso, A.; Roudriguez Manjas, L.; Illario, M.; Roller-Wirnsberger, R.E. Educational strategies to train health care professionals across the education continuum on the process of frailty prevention and frailty management: A systematic review. Aging Clin. Exp. Res., 2018, 30(12), 1409-1415.
[http://dx.doi.org/10.1007/s40520-018-0918-9] [PMID: 29476480]
[157]
Faye, A.S.; Wen, T.; Soroush, A.; Ananthakrishnan, A.N.; Ungaro, R.; Lawlor, G.; Attenello, F.J.; Mack, W.J.; Colombel, J.F.; Lebwohl, B. Increasing prevalence of frailty and its association with readmission and mortality among hospitalized patients with IBD. Dig. Dis. Sci., 2021, 66(12), 4178-4190.
[http://dx.doi.org/10.1007/s10620-020-06746-w] [PMID: 33385264]
[158]
Rodríguez-Mañas, L.; Rodríguez-Sánchez, B.; Carnicero, J.A.; Rueda, R.; García-Garcia, F.J.; Pereira, S.L.; Sulo, S. Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults. Clin. Nutr., 2021, 40(3), 1192-1198.
[http://dx.doi.org/10.1016/j.clnu.2020.07.032] [PMID: 32826110]
[159]
Tański, W.; Wójciga, J.; Jankowska-Polańska, B. Association between malnutrition and quality of life in elderly patients with rheumatoid arthritis. Nutrients, 2021, 13(4), 1259.
[http://dx.doi.org/10.3390/nu13041259] [PMID: 33921207]
[160]
Emmerton, D.; Abdelhafiz, A. Newer anti-diabetic therapies with low hypoglycemic risk-potential advantages for frail older people. Hosp. Pract., 2021, 49(3), 164-175.
[http://dx.doi.org/10.1080/21548331.2021.1905414] [PMID: 33729898]
[161]
Fotuhi, M.; Hachinski, V.; Whitehouse, P.J. Changing perspectives regarding late-life dementia. Nat. Rev. Neurol., 2009, 5(12), 649-658.
[http://dx.doi.org/10.1038/nrneurol.2009.175] [PMID: 19918254]
[162]
Arvanitakis, Z.; Leurgans, S.E.; Barnes, L.L.; Bennett, D.A.; Schneider, J.A. Microinfarct pathology, dementia, and cognitive systems. Stroke, 2011, 42(3), 722-727.
[http://dx.doi.org/10.1161/STROKEAHA.110.595082] [PMID: 21212395]
[163]
Sonnen, J.A.; Larson, E.B.; Crane, P.K.; Haneuse, S.; Li, G.; Schellenberg, G.D.; Craft, S.; Leverenz, J.B.; Montine, T.J. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann. Neurol., 2007, 62(4), 406-413.
[http://dx.doi.org/10.1002/ana.21208] [PMID: 17879383]
[164]
McKeith, I.; O’Brien, J.; Walker, Z.; Tatsch, K.; Booij, J.; Darcourt, J.; Padovani, A.; Giubbini, R.; Bonuccelli, U.; Volterrani, D.; Holmes, C.; Kemp, P.; Tabet, N.; Meyer, I.; Reininger, C. Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: A phase III, multicentre study. Lancet Neurol., 2007, 6(4), 305-313.
[http://dx.doi.org/10.1016/S1474-4422(07)70057-1] [PMID: 17362834]
[165]
Bocti, C.; Black, S.; Frank, C. Management of dementia with a cerebrovascular component. Alzheimers Dement., 2007, 3(4), 398-403.
[http://dx.doi.org/10.1016/j.jalz.2007.07.009] [PMID: 19595960]
[166]
Jansen, S.; Ball, L.; Desbrow, B.; Morgan, K.; Moyle, W.; Hughes, R. Nutrition and dementia care: Informing dietetic practice. Nutr. Diet., 2015, 72(1), 36-46.
[http://dx.doi.org/10.1111/1747-0080.12144]
[167]
Zesiewicz, T.A.; Sullivan, K.L.; Arnulf, I.; Chaudhuri, K.R.; Morgan, J.C.; Gronseth, G.S.; Miyasaki, J.; Iverson, D.J.; Weiner, W.J. Practice Parameter: treatment of nonmotor symptoms of Parkinson disease: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology, 2010, 74(11), 924-931.
[http://dx.doi.org/10.1212/WNL.0b013e3181d55f24] [PMID: 20231670]
[168]
Postuma, R.B.; Gagnon, J.-F.; Montplaisir, J.Y. REM sleep behavior disorder and prodromal neurodegeneration – where are we headed? Tremor Hyperkinet. Mov., 2013, 3, 03.
[169]
Vidoni, E.D.; Perales, J.; Alshehri, M.; Giles, A.M.; Siengsukon, C.F.; Burns, J.M. Aerobic exercise sustains performance of instrumental activities of daily living in early-stage alzheimer disease. J. Geriatr. Phys., 2019, 42(3), E129-E134.
[http://dx.doi.org/10.1519/JPT.0000000000000172] [PMID: 29286983]
[170]
Miyasaki, J.M.; Shannon, K.; Voon, V. American academy of neurology review: Report of the quality standards subcommittee of the psychosis, and dementia in parkinson disease (an evidence-based practice parameter): Evaluation and treatment of depression. Neurology, 2006, 66(7), 996-1002.
[http://dx.doi.org/10.1212/01.wnl.0000215428.46057.3d] [PMID: 16606910]
[171]
Wang, H.F.; Yu, J.T.; Tang, S.W.; Jiang, T.; Tan, C.C.; Meng, X.F.; Wang, C.; Tan, M.S.; Tan, L. Efficacy and safety of cholinesterase inhibitors and memantine in cognitive impairment in Parkinson’s disease, Parkinson’s disease dementia, and dementia with Lewy bodies: systematic review with meta-analysis and trial sequential analysis. J. Neurol. Neurosurg. Psychiatry, 2015, 86(2), 135-143.
[http://dx.doi.org/10.1136/jnnp-2014-307659] [PMID: 24828899]
[172]
Stinton, C.; McKeith, I.; Taylor, J.P.; Lafortune, L.; Mioshi, E.; Mak, E.; Cambridge, V.; Mason, J.; Thomas, A.; O’Brien, J.T. Pharmacological management of lewy body dementia: A systematic review and meta-analysis. Am. J. Psychiatry, 2015, 172(8), 731-742.
[http://dx.doi.org/10.1176/appi.ajp.2015.14121582] [PMID: 26085043]
[173]
Dent, E.; Morley, J.E.; Cruz-Jentoft, A.J.; Woodhouse, L.; Rodríguez-Mañas, L.; Fried, L.P.; Woo, J.; Aprahamian, I.; Sanford, A.; Lundy, J.; Landi, F.; Beilby, J.; Martin, F.C.; Bauer, J.M.; Ferrucci, L.; Merchant, R.A.; Dong, B.; Arai, H.; Hoogendijk, E.O.; Won, C.W.; Abbatecola, A.; Cederholm, T.; Strandberg, T.; Gutiérrez Robledo, L.M.; Flicker, L.; Bhasin, S.; Aubertin-Leheudre, M.; Bischoff-Ferrari, H.A.; Guralnik, J.M.; Muscedere, J.; Pahor, M.; Ruiz, J.; Negm, A.M.; Reginster, J.Y.; Waters, D.L.; Vellas, B. Physical frailty: ICFSR international clinical practice guidelines for identification and management. J. Nutr. Health Aging, 2019, 23(9), 771-787.
[http://dx.doi.org/10.1007/s12603-019-1273-z] [PMID: 31641726]
[174]
Bruyère, O.; Cavalier, E.; Reginster, J.Y. Vitamin D and osteosarcopenia: An update from epidemiological studies. Curr. Opin. Clin. Nutr. Metab. Care, 2017, 20(6), 498-503.
[http://dx.doi.org/10.1097/MCO.0000000000000411] [PMID: 28806178]
[175]
Wang, H-K.; Hung, C-M.; Lin, S-H.; Tai, Y.C.; Lu, K.; Liliang, P.C.; Lin, C.W.; Lee, Y.C.; Fang, P.H.; Chang, L.C.; Li, Y.C. Increased risk of hip fractures in patients with dementia: A nationwide population-based study. BMC Neurol., 2014, 14(1), 175.
[http://dx.doi.org/10.1186/s12883-014-0175-2] [PMID: 25213690]
[176]
Chang, N-T.; Yang, N-P.; Chou, P. Incidence, risk factors and consequences of falling injuries among the community-dwelling elderly in Shihpai, Taiwan. Aging Clin. Exp. Res., 2010, 22(1), 70-77.
[http://dx.doi.org/10.1007/BF03324818] [PMID: 19934620]
[177]
Netz, Y.; Axelrad, S.; Argov, E. Group physical activity for demented older adults feasibility and effectiveness. Clin. Rehabil., 2007, 21(11), 977-986.
[http://dx.doi.org/10.1177/0269215507078318] [PMID: 17984150]
[178]
Wharton, TC; Ford, BK What is known about dementia care recipient violence and aggression against caregivers? Routledge, 2014, 57(5), 460-477.
[http://dx.doi.org/10.1080/01634372.2014.882466]
[179]
O’Leary, D.; Jyringi, D.; Sedler, M. Childhood conduct problems, stages of Alzheimer’s disease, and physical aggression against caregivers. Int. J. Geriatr. Psychiatry, 2005, 20(5), 401-405.
[http://dx.doi.org/10.1002/gps.1293] [PMID: 15852459]
[180]
Ryden, M.B. Aggressive behavior in persons with dementia who live in the community. Alzheimer Dis. Assoc. Disord., 1988, 2(4), 342-355.
[http://dx.doi.org/10.1097/00002093-198802040-00003] [PMID: 3196468]
[181]
Enmarker, I.; Olsen, R.; Hellzen, O. Management of person with dementia with aggressive and violent behaviour: A systematic literature review. Int. J. Older People Nurs., 2011, 6(2), 153-162.
[http://dx.doi.org/10.1111/j.1748-3743.2010.00235.x] [PMID: 21539720]
[182]
Puts, M.T.E.; Toubasi, S.; Andrew, M.K.; Ashe, M.C.; Ploeg, J.; Atkinson, E.; Ayala, A.P.; Roy, A.; Rodríguez Monforte, M.; Bergman, H.; McGilton, K. Interventions to prevent or reduce the level of frailty in community-dwelling older adults: A scoping review of the literature and international policies. Age Ageing, 2017, 46(3), 383-392.
[http://dx.doi.org/10.1093/ageing/afw247] [PMID: 28064173]
[183]
Cesari, M.; Vellas, B.; Hsu, F-C.; Newman, A.B.; Doss, H.; King, A.C.; Manini, T.M.; Church, T.; Gill, T.M.; Miller, M.E.; Pahor, M. A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study. Med. Sci., 2015, 70(2), 216-222.
[http://dx.doi.org/10.1093/gerona/glu099] [PMID: 25387728]
[184]
Cummings, J.; Lai, T-J.; Hemrungrojn, S.; Mohandas, E.; Yun Kim, S.; Nair, G.; Dash, A. Role of donepezil in the management of neuropsychiatric symptoms in Alzheimer’s Disease and Dementia with Lewy Bodies. CNS Neurosci. Ther., 2016, 22(3), 159-166.
[http://dx.doi.org/10.1111/cns.12484] [PMID: 26778658]
[185]
McDermott, C.L.; Gruenewald, D.A. Pharmacologic management of agitation in patients with Dementia. Curr. Geriatr. Rep., 2019, 8(1), 1-11.
[http://dx.doi.org/10.1007/s13670-019-0269-1] [PMID: 31341757]
[186]
Kaufmann, C.P.; Tremp, R.; Hersberger, K.E.; Lampert, M.L. Inappropriate prescribing: A systematic overview of published assessment tools. Eur. J. Clin. Pharmacol., 2014, 70(1), 1-11.
[http://dx.doi.org/10.1007/s00228-013-1575-8] [PMID: 24019054]
[187]
Denison, H.J.; Cooper, C.; Sayer, A.A.; Robinson, S.M. Prevention and optimal management of sarcopenia: A review of combined exercise and nutrition interventions to improve muscle outcomes in older people. Clin. Interv. Aging, 2015, 10, 859-869.
[PMID: 25999704]
[188]
Ble, A.; Cherubini, A.; Volpato, S.; Bartali, B.; Walston, J.D.; Windham, B.G.; Bandinelli, S.; Lauretani, F.; Guralnik, J.M.; Ferrucci, L. Lower plasma vitamin E levels are associated with the frailty syndrome: the InCHIANTI study. J. Gerontol. A Biol. Sci. Med. Sci., 2006, 61(3), 278-283.
[http://dx.doi.org/10.1093/gerona/61.3.278] [PMID: 16567378]
[189]
Abdelhamid, A.; Bunn, D.; Copley, M.; Cowap, V.; Dickinson, A.; Gray, L.; Howe, A.; Killett, A.; Lee, J.; Li, F.; Poland, F.; Potter, J.; Richardson, K.; Smithard, D.; Fox, C.; Hooper, L. Effectiveness of interventions to directly support food and drink intake in people with dementia: systematic review and meta-analysis. BMC Geriatr., 2016, 16(1), 26.
[http://dx.doi.org/10.1186/s12877-016-0196-3] [PMID: 26801619]
[190]
Volkert, D.; Berner, Y.N.; Berry, E.; Cederholm, T.; Coti Bertrand, P.; Milne, A.; Palmblad, J.; Schneider, S.; Sobotka, L.; Stanga, Z.; Lenzen-Grossimlinghaus, R.; Krys, U.; Pirlich, M.; Herbst, B.; Schütz, T.; Schröer, W.; Weinrebe, W.; Ockenga, J.; Lochs, H. ESPEN guidelines on enteral nutrition: Geriatrics. Clin. Nutr., 2006, 25(2), 330-360.
[http://dx.doi.org/10.1016/j.clnu.2006.01.012] [PMID: 16735082]
[191]
Islam, F.; Bibi, S.; Meem, A.F.K.; Islam, M.M.; Rahaman, M.S.; Bepary, S.; Rahman, M.M.; Rahman, M.M.; Elzaki, A.; Kajoak, S.; Osman, H.; ElSamani, M.; Khandaker, M.U.; Idris, A.M.; Emran, T.B. Natural bioactive molecules: An alternative approach to the treatment and control of COVID-19. Int. J. Mol. Sci., 2021, 22(23), 12638.
[http://dx.doi.org/10.3390/ijms222312638] [PMID: 34884440]
[192]
Baldwin, R Residential aged care policy in Australia–are we learning from evidence? 2015, 74(2), 128-141.
[http://dx.doi.org/10.1111/1467-8500.12131]
[193]
Berry, C.P. Austerity, ageing and the financialisation of pensions policy in the UK. Br. Polit., 2016, 1(1), 2-25.
[http://dx.doi.org/10.1057/bp.2014.19]
[194]
Lössbroek, J.; Lancee, B.; Van Der Lippe, T.; Schippers, J. Understanding old-age adaptation policies in Europe: The influence of profit, principles and pressures. Ageing Soc., 2019, 39(5), 924-950.
[http://dx.doi.org/10.1017/S0144686X17001295]
[195]
Hussein, S.; Ismail, M. Ageing and elderly care in the arab region: Policy challenges and opportunities. Ageing Int., 2017, 42(3), 274-289.
[http://dx.doi.org/10.1007/s12126-016-9244-8] [PMID: 28890585]
[196]
Nan, Y.; Feng, T.; Hu, Y.; Qi, X. Understanding aging policies in China: A bibliometric analysis of policy documents. Int. J. Environ. Res. Public Health, 2020, 17(16), 5956.
[http://dx.doi.org/10.3390/ijerph17165956] [PMID: 32824512]
[197]
Zhang, X.; Yang, F. Rural informatization policy evolution in China: A bibliometric study. Sci., 2019, 120(1), 129-153.

Rights & Permissions Print Cite
Article Metrics
53
1
© 2024 Bentham Science Publishers | Privacy Policy