Abstract
Chemotaxis is essential for many biological processes. Much of our understanding of the mechanisms underlying chemotaxis is based on a variety of in vitro assays. We review these assays, dividing them into groups depending on the process used to generate the gradient. We describe how each method works, its strengths and limitations, and provide some information about the kinds of cells that have been studied with each assay.
Combinatorial Chemistry & High Throughput Screening
Title: Assays for Eukaryotic Cell Chemotaxis
Volume: 12 Issue: 6
Author(s): Zac Pujic, Duncan Mortimer, Julia Feldner and Geoffrey J. Goodhill
Affiliation:
Abstract: Chemotaxis is essential for many biological processes. Much of our understanding of the mechanisms underlying chemotaxis is based on a variety of in vitro assays. We review these assays, dividing them into groups depending on the process used to generate the gradient. We describe how each method works, its strengths and limitations, and provide some information about the kinds of cells that have been studied with each assay.
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Cite this article as:
Pujic Zac, Mortimer Duncan, Feldner Julia and Goodhill J. Geoffrey, Assays for Eukaryotic Cell Chemotaxis, Combinatorial Chemistry & High Throughput Screening 2009; 12 (6) . https://dx.doi.org/10.2174/138620709788681952
DOI https://dx.doi.org/10.2174/138620709788681952 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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