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Current Cancer Therapy Reviews

Editor-in-Chief

ISSN (Print): 1573-3947
ISSN (Online): 1875-6301

Chronic Eosinophilic Leukemia, Not Otherwise Specified (CEL, NOS)

Author(s): Cherie H. Dunphy

Volume 8, Issue 1, 2012

Page: [30 - 34] Pages: 5

DOI: 10.2174/157339412799462512

Price: $65

Abstract

Chronic eosinophilic leukemia, NOS (CEL, NOS) is considered a myeloproliferative neoplasm and is defined as a clonal proliferation of eosinophil precursors. This review presents the definition and characteristic cytomorphological, immunophenotypic, cytogenetic, and molecular features of CEL, NOS and discusses in depth the differential diagnoses. Following this presentation, the review then focuses on therapeutic approaches, including targeted therapy.

Keywords: Chronic eosinophilic leukemia, idiopathic hypereosinophilia, clonality


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