Abstract
Epidemiologic studies have provided important clues about the etiology, prognosis and options for prevention and treatment of AD, and sub-clinical changes in cognition and brain structure. A brief review is given of what we have learned from epidemiologic studies of risk factors and natural history. This is followed by a discussion of how these findings could inform the design of basic research strategies that may further the translation of bench science to the clinic and public health arena.
Keywords: cardiovascular risk factors, Diabetes, magnetic resonance images, CNS, cognitive impairment
Current Alzheimer Research
Title: Next Steps in Alzheimers Disease Research: Interaction between Epidemiology and Basic Science
Volume: 4 Issue: 2
Author(s): Lenore J. Launer
Affiliation:
Keywords: cardiovascular risk factors, Diabetes, magnetic resonance images, CNS, cognitive impairment
Abstract: Epidemiologic studies have provided important clues about the etiology, prognosis and options for prevention and treatment of AD, and sub-clinical changes in cognition and brain structure. A brief review is given of what we have learned from epidemiologic studies of risk factors and natural history. This is followed by a discussion of how these findings could inform the design of basic research strategies that may further the translation of bench science to the clinic and public health arena.
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Cite this article as:
Launer J. Lenore, Next Steps in Alzheimers Disease Research: Interaction between Epidemiology and Basic Science, Current Alzheimer Research 2007; 4 (2) . https://dx.doi.org/10.2174/156720507780362155
DOI https://dx.doi.org/10.2174/156720507780362155 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
Call for Papers in Thematic Issues
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Aims and Scope: Introduction: Alzheimer's disease (AD) poses a significant global health challenge, with an increasing prevalence that demands concerted efforts to advance our understanding and strategies for prevention, diagnosis, treatment, and rehabilitation. This thematic issue aims to bring together cutting-edge research and innovative approaches from multidisciplinary perspectives to address ...read more
Alzheimer's Disease Drug Development
Alzheimer's disease is a progressive neurodegenerative disorder that affects millions of people worldwide. Despite decades of research, no cure or disease-modifying treatment is available yet. Therefore, the need for developing effective therapies to treat Alzheimer's disease is an urgent matter. This special issue aims to provide a comprehensive overview of ...read more
Current updates on the Role of Neuroinflammation in Neurodegenerative Disorders
Neuroinflammation is an invariable hallmark of chronic and acute neurodegenerative disorders and has long been considered a potential drug target for Alzheimer?s disease (AD) and dementia. Significant evidence of inflammatory processes as a feature of AD is provided by the presence of inflammatory markers in plasma, CSF and postmortem brain ...read more
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Alzheimer's disease (AD) poses a significant global health challenge, with an increasing number of individuals affected yearly. Deep learning, a subfield of artificial intelligence, has shown immense potential in various domains, including healthcare. This thematic issue of Current Alzheimer Research explores the application of deep learning techniques in advancing our ...read more
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