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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Prospects for Combinatorial Chemistry in the Agrosciences

Author(s): Stephen D. Lindell and Jurgen Scherkenbeck

Volume 8, Issue 7, 2005

Page: [555 - 562] Pages: 8

DOI: 10.2174/138620705774575319

Price: $65

Abstract

The recent progress and future prospects for the successful application of combinatorial chemistry and high throughput screening within the agrochemical lead discovery process are outlined and discussed. Solid and solution phase library synthesis technologies are reviewed and compared, and the role and importance of bioavailability, diversity and virtual screening in rational library design are detailed.

Keywords: combinatorial library, bioavailability, diversity, virtual screening, target docking, fragment assembly


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