Abstract
Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.
Keywords: Endothelial cell, endothelial to mesenchymal transition, EndMT, TGFβ, FGF.
Current Drug Targets
Title:Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition
Volume: 17 Issue: 15
Author(s): Pei-Yu Chen and Michael Simons
Affiliation:
Keywords: Endothelial cell, endothelial to mesenchymal transition, EndMT, TGFβ, FGF.
Abstract: Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.
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Cite this article as:
Chen Pei-Yu and Simons Michael, Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition, Current Drug Targets 2016; 17 (15) . https://dx.doi.org/10.2174/1389450117666160502151308
DOI https://dx.doi.org/10.2174/1389450117666160502151308 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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