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An Update on SARS-CoV-2: Damage-response Framework, Potential Therapeutic Avenues and the Impact of Nanotechnology on COVID-19 Therapy

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Epidemiology of COVID-19

Author(s): Anitha Sriram, Yojana Bhor, Srushti Mahajan, Rahul Kumar, Saurabh Srivastava, Dharmendra Kumar Khatri, Shashi Bala Singh and Pankaj Kumar Singh * .

Pp: 67-90 (24)

DOI: 10.2174/9789815039863122010007

* (Excluding Mailing and Handling)

Abstract

The epidemiology of COVID-19 infection will be understood by the relationship between the intensity of action on public well-being and the rate of its transmission control. The virus is a chemical substance that is vulnerable until it invades the living body. The molecular assembly of the virus contains RNA genome and proteins. When 2019-nCoV enters the host cell of the living body, it continues its progeny by the replication process. It starts to make molecular assemblies for every new virion produced through replication and transcription. Though the incubation time is accounted for to range between 1 to 14 days, the median incubation period is 5 days. According to a recent survey on COVID-19 patients, 80 percent of patients are asymptomatic. This book chapter describes the life cycle and spread of 2019-nCoV, CFR, clinical manifestations, diagnosis, and prevention of COVID-19. 

Keywords: 2019-nCoV, COVID-19, HRCT, Life cycle, Prevention, Symptoms, Transmission.

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