Steroids and their Medicinal Potential

Destructive Effects of Steroidal Drug Abuse and their Immunological Impact

Author(s): Parimalanandhini Duraisamy, Sangeetha Ravi, Mahalakshmi Krishnan, Livya Catherene Martin, Beulaja Manikandan, Sundaram Janarthanan and Ramar Manikandan * .

Pp: 286-308 (23)

DOI: 10.2174/789815049336123010013

* (Excluding Mailing and Handling)


Steroidal drugs are synthetic in nature that are closely identical to naturally produced hormones in our body such as cortisol and testosterone. They are lifesavers for several threatening medical conditions. They are currently in wide use for the treatment of various inflammatory diseases since they are known to involve in suppressing the immune system resulting in a reduced inflammatory process. They are produced in different forms and do not cause any major side effects when consumed at low doses. However, occasionally they lead to perilous side effects when taken in appropriate doses that lead to mental health problems, high blood pressure, diabetes, osteoporosis, etc. Practices such as the uptake of illicit anabolic steroids and corticosteroid drugs without an appropriate prescription can potentially lead to fatal side effects. Anabolic steroids are performance and image-enhancing drugs that were once viewed as predicament associated with bodybuilders and have now become a widespread problem throughout our society including children. Dietary supplements which act as steroidal precursors also promote medical consequences that are similar to steroids and the absence of such awareness in our society leads to varied difficulties in our current lifestyle. The increasing concern about possible health hazards in association with abusive steroid drug uptake should be addressed with strict measures. It is important to educate our society about the hazardous effects of steroidal drug abuse and the precautions that need to be carried out while using them. This chapter highlights different types of steroid drugs that are currently in use and the deleterious side effects caused by their abusive use. Potential treatments for their withdrawal and preventive measures will also be addressed in detail. 

Keywords: Anabolic steroids, Corticosteroids, Drug abuse, Inflammation, Steroidal drugs.

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