Novel Nanotechnological Therapy Approaches to Glioblastoma

Abstract

Glioblastoma is one of the most aggressive and deadly types of cancer. The blood-brain barrier is the biggest obstacle to overcome in glioblastoma treatment. Nanomedicine, which describes the use of nanostructures in medicine, has significant potential for glioblastoma. Nanomedicine provides advantages in crossing the blood-brain barrier, increasing the amount and effectiveness of drugs reaching the cancer site, monitoring diagnosis and treatment through imaging agents, and increasing the effectiveness of treatments in combination applications. This chapter reviews current nanotechnology research in glioblastoma over the past few years.

Keywords: Blood-brain barrier, Cancer, Chemotherapy, Cubosome, Dendrimers, Glioblastoma, In vitro, In vivo, Lipid nanoparticle, Liposomes, Micelles, Nanodiamonds, Nanomedicine, Nanoparticles, Nanostructures, Nanotubes, PAMAM, Polymersomes, Quantum dots, Radiotherapy.