Abstract
The double addition of organolithium compounds and allylzinc bromide to the imines prepared from (R,R)-1,2- diaminocyclohexane by condensation with aromatic and heteroaromatic aldehydes gave secondary diamines with high yields and diastereoselectivities apart for the reaction of 2-pyridinealdehyde derivative which occurred with low to moderate stereocontrol.
Keywords: Amine, 1,2-diaminocyclohexane, diastereoselectivity, imine, organometallic reagents
Letters in Organic Chemistry
Title: Diastereoselective Addition of Organometallic Reagents to Diimines Derived from (R,R)-1,2-Diaminocyclohexane and Aromatic Aldehydes
Volume: 6 Issue: 6
Author(s): Diego Savoia, Andrea Gualandi and Marco Bandini
Affiliation:
Keywords: Amine, 1,2-diaminocyclohexane, diastereoselectivity, imine, organometallic reagents
Abstract: The double addition of organolithium compounds and allylzinc bromide to the imines prepared from (R,R)-1,2- diaminocyclohexane by condensation with aromatic and heteroaromatic aldehydes gave secondary diamines with high yields and diastereoselectivities apart for the reaction of 2-pyridinealdehyde derivative which occurred with low to moderate stereocontrol.
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Cite this article as:
Savoia Diego, Gualandi Andrea and Bandini Marco, Diastereoselective Addition of Organometallic Reagents to Diimines Derived from (R,R)-1,2-Diaminocyclohexane and Aromatic Aldehydes, Letters in Organic Chemistry 2009; 6 (6) . https://dx.doi.org/10.2174/157017809789124948
DOI https://dx.doi.org/10.2174/157017809789124948 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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