Abstract
Baculovirus has been widely utilized as a protein production tool in insect cells for nearly 3 decades and has captured growing interests as a vector for gene delivery into mammalian cells and animals over the past decade. This review summarizes important patents pertaining to the use of baculovirus for insect cell infection and mammalian cell transduction, with special emphasis on the vector development, new applications and downstream processing.
Keywords: Baculovirus, expression system, insect cell, mammalian cell, vaccine, mammalian cell transduction, downstream processing, nucleopolyhedrovirus, replication, human interferon, DNA cloning capacity, Rous Sarcoma Virus (RSV), cytomegalovirus (CMV), long terminal repeat (LTR) promoter, eucaryotic proteins, delivery of vaccine immunogens, polyadenylation sequence
Recent Patents on Biotechnology
Title: Recent Patents on the Baculovirus Systems
Volume: 5 Issue: 1
Author(s): Shih-Yeh Lin, Guan-Yu Chen and Yu-Chen Hu
Affiliation:
Keywords: Baculovirus, expression system, insect cell, mammalian cell, vaccine, mammalian cell transduction, downstream processing, nucleopolyhedrovirus, replication, human interferon, DNA cloning capacity, Rous Sarcoma Virus (RSV), cytomegalovirus (CMV), long terminal repeat (LTR) promoter, eucaryotic proteins, delivery of vaccine immunogens, polyadenylation sequence
Abstract: Baculovirus has been widely utilized as a protein production tool in insect cells for nearly 3 decades and has captured growing interests as a vector for gene delivery into mammalian cells and animals over the past decade. This review summarizes important patents pertaining to the use of baculovirus for insect cell infection and mammalian cell transduction, with special emphasis on the vector development, new applications and downstream processing.
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Cite this article as:
Lin Shih-Yeh, Chen Guan-Yu and Hu Yu-Chen, Recent Patents on the Baculovirus Systems, Recent Patents on Biotechnology 2011; 5 (1) . https://dx.doi.org/10.2174/187220811795655904
DOI https://dx.doi.org/10.2174/187220811795655904 |
Print ISSN 1872-2083 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4012 |
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