Abstract
The use and indications of anti-vascular endothelial growth factors (VEGF) are rapidly expanding, evolving and undergoing refinement in retinal diseases. This manuscript attempts to perform a critical appraisal of the diaspora of limited information available on the non- traditional applications (outside of AMD, DR and vascular occlusive diseases) and synthesize a review. As with any newer drug, only longitudinal studies will determine the true inherent value no matter how broad the current popular appeal appears to be due to very positive press. Although these drugs appear to be very effective in conventional applications, it is wise to deliberate prior to non-conventional use.
Keywords: Bevacizumab, choroidal neovascularization, myopia, retinopathy of prematurity, Vascular endothelial growth factor, VEGF, Coloboma, Angioid streaks, Choroidal rupture, chorioretinopathy
Current Drug Therapy
Title:Utility of Non-Conventional Applications of Anti-VEGF Treatment in Selected Retinal Diseases
Volume: 7 Issue: 2
Author(s): Rebecca A. Manning, Charles P. Richards, Kishan Govind and Shree K. Kurup
Affiliation:
Keywords: Bevacizumab, choroidal neovascularization, myopia, retinopathy of prematurity, Vascular endothelial growth factor, VEGF, Coloboma, Angioid streaks, Choroidal rupture, chorioretinopathy
Abstract: The use and indications of anti-vascular endothelial growth factors (VEGF) are rapidly expanding, evolving and undergoing refinement in retinal diseases. This manuscript attempts to perform a critical appraisal of the diaspora of limited information available on the non- traditional applications (outside of AMD, DR and vascular occlusive diseases) and synthesize a review. As with any newer drug, only longitudinal studies will determine the true inherent value no matter how broad the current popular appeal appears to be due to very positive press. Although these drugs appear to be very effective in conventional applications, it is wise to deliberate prior to non-conventional use.
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Cite this article as:
A. Manning Rebecca, P. Richards Charles, Govind Kishan and K. Kurup Shree, Utility of Non-Conventional Applications of Anti-VEGF Treatment in Selected Retinal Diseases, Current Drug Therapy 2012; 7 (2) . https://dx.doi.org/10.2174/157488512800676057
DOI https://dx.doi.org/10.2174/157488512800676057 |
Print ISSN 1574-8855 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3903 |
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