Abstract
In this prospective, randomized, double-blinded study, clonidine was found an efficient adjunct to local anesthetics for increasing the intensity of axillary brachial plexus block. Similar clonidine dose had no such effect when administered intramuscularly, suggesting a local, neural effect. Blood absorption was similar in both cases, leading to central action as sedation.
Keywords: Adrenergic agonists, adrenergic a-agonists, anesthesia, conduction, nerve block, pharmacology, plasma clonidine concentration
Letters in Drug Design & Discovery
Title: Improved Sensory Blockade by Clonidine Added to Axillary Block Solution. Resulting Plasma Clonidine Concentration
Volume: 3 Issue: 2
Author(s): Jean-Marc Bernard
Affiliation:
Keywords: Adrenergic agonists, adrenergic a-agonists, anesthesia, conduction, nerve block, pharmacology, plasma clonidine concentration
Abstract: In this prospective, randomized, double-blinded study, clonidine was found an efficient adjunct to local anesthetics for increasing the intensity of axillary brachial plexus block. Similar clonidine dose had no such effect when administered intramuscularly, suggesting a local, neural effect. Blood absorption was similar in both cases, leading to central action as sedation.
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Cite this article as:
Bernard Jean-Marc, Improved Sensory Blockade by Clonidine Added to Axillary Block Solution. Resulting Plasma Clonidine Concentration, Letters in Drug Design & Discovery 2006; 3 (2) . https://dx.doi.org/10.2174/157018006775789739
DOI https://dx.doi.org/10.2174/157018006775789739 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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