Abstract
Lanthanide complexes have been used for fluorescent labels to the wide variety of analytical methods including high performance liquid chromatography, immunoassay, and fluorescent imaging with time-resolved fluorometric measurements. Introduction of a time-resolved fluorometric measurement has been permitted the easy distinction of a specific long-lived fluorescence signal from short-lived natural background fluorescence present in most biological samples, reaction wells and optical components. Recently, new fluorescent labels and new instruments have been reported for timeresolved fluorescence including high performance liquid chromatography as in environmental analysis as river water, clinical chemistry as allergen assay, and a biochemical analysis as in staining method of proteins on polyacrylamide gel. The time-resolved fluorometric detection methods using new fluorescent labels improved the detection sensitivity compared to those of previously-described methods. This paper reviews those developments of applications of lanthanide fluorescent labels for various purposes: time-resolved fluorometric high performance liquid chromatography, timeresolved fluorescent immunoassay, and protein staining in recent years.
Keywords: Lanthanide complex, Fluorescent label, Time-resolved fluorescence, High-performance liquid hromatography, Immunoassay, Electrophoresis
Call for Papers in Thematic Issues
Advancements in biomedicine, corrosion inhibition/monitoring, and lubrication of carbon dots
Carbon dots, a class of carbon-based nanomaterials, have garnered substantial interest in various scientific and engineering fields due to their unique properties, including excellent optical properties, outstanding biocompatibility, easy preparation, good dispersity, ultrasmall size, low toxicity and environmental friendliness. This special issue of Current Analytical Chemistry aims to showcase cutting-edge ...read more
Advances in Microfluidic and Sensing Technologies of Biofluids.
Detection of biological fluids is an important means to assess human health and diagnose diseases. Currently, research on blood is relatively mature and widely applied in the medical field. With the development and advancement of microfluidic technology and novel detection methods, attention has turned to human physiological fluids such as ...read more
Analytical methods for environmental and food analysis
In recent years, the study of the chemical composition of food and the environment depends on analytical methods in order to acquire information about the chemical composition, processing, quality control and contamination of soil, water, air, plants and foods, aspects very important for food safety and environmental quality control. There ...read more
Applications of artificial intelligence in chemical analysis
Artificial intelligence (AI) has demonstrated its versatility in almost all scientific fields, especially analytical chemistry, which is leading the way in the integration of AI. According to Chemical Abstract Services, one of the major disciplines contributing to AI-related publications and patents is analytical chemistry. That?s because techniques such as deep ...read more
Related Journals
Anti-Cancer Agents in Medicinal Chemistry
Current Computer-Aided Drug Design
Current Bioactive Compounds
Combinatorial Chemistry & High Throughput Screening
Current Medicinal Chemistry
The Natural Products Journal
Current Catalysis
Current Chinese Chemistry
Current Chinese Science
Current Topics in Chemistry
Related Books
Botanicals and Natural Bioactives: Prevention and Treatment of Diseases
Biosurfactants: A Boon to Healthcare, Agriculture & Environmental Sustainability
Frontiers in Computational Chemistry
Advances in Dye Degradation
Biological and Medical Significance of Chemical Elements
Frontiers In Medicinal Chemistry
Advances in Organic Synthesis
Frontiers in Natural Product Chemistry
Recent Advances in Analytical Techniques
Advanced Catalysts Based on Metal-organic Frameworks (Part 2)
12