Abstract
Metabolic syndrome places patients at high risk to many other health problems, as their bodies are in a perpetual state pro-inflammation and pro-thrombosis. In many cases, a regulated diet and increased exercise is sufficient in rectifying their condition, however for many patients, drug intervention is necessary. In recent years, calorie restriction has been shown to improve the health of patients afflicted with aging-related diseases, specifically those associated with metabolic syndrome, and researchers are now exploring drugs that mimic calorie restriction. Resveratrol mimics a calorie restricted diet as it has been shown to attenuate health benefits, including anti-platelet aggregation, vasorelaxation, atherosclerosis suppression, and lipid metabolism similar to a calorie restricted diet. Additionally, it modulates many of the pathways associated with metabolic syndrome, leading researchers to believe it has potential as a burgeoning therapeutic approach.
Keywords: Resveratrol, metabolic syndrome, calorie restriction, SIRT1
Current Nutrition & Food Science
Title: Resveratrol as a Supplemental Therapeutic in Cardiovascular and Metabolic Syndromes: A Critical Review
Volume: 5 Issue: 1
Author(s): Stephen Esker, Antora Banerjee, Tessa M. Simone, Christine A. Gallati and Shaker A. Mousa
Affiliation:
Keywords: Resveratrol, metabolic syndrome, calorie restriction, SIRT1
Abstract: Metabolic syndrome places patients at high risk to many other health problems, as their bodies are in a perpetual state pro-inflammation and pro-thrombosis. In many cases, a regulated diet and increased exercise is sufficient in rectifying their condition, however for many patients, drug intervention is necessary. In recent years, calorie restriction has been shown to improve the health of patients afflicted with aging-related diseases, specifically those associated with metabolic syndrome, and researchers are now exploring drugs that mimic calorie restriction. Resveratrol mimics a calorie restricted diet as it has been shown to attenuate health benefits, including anti-platelet aggregation, vasorelaxation, atherosclerosis suppression, and lipid metabolism similar to a calorie restricted diet. Additionally, it modulates many of the pathways associated with metabolic syndrome, leading researchers to believe it has potential as a burgeoning therapeutic approach.
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Cite this article as:
Esker Stephen, Banerjee Antora, Simone M. Tessa, Gallati A. Christine and Mousa A. Shaker, Resveratrol as a Supplemental Therapeutic in Cardiovascular and Metabolic Syndromes: A Critical Review, Current Nutrition & Food Science 2009; 5 (1) . https://dx.doi.org/10.2174/157340109787314785
DOI https://dx.doi.org/10.2174/157340109787314785 |
Print ISSN 1573-4013 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3881 |
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