Abstract
Background: Three types of necrosis characterize MI: coagulation necrosis, typically due to a coronarogenic mechanism, coagulative myocytolysis with formation of contract bands as an effect of sympathetic nervous system and adrenergic stimulation, and colliquative myocytolysis, characterized by myocardial fiber lysis, which is a close result of hydrolytic enzyme activity deriving from the material reaching the infarct area.
Methods: Although a multifactorial etiology may be identified, nevertheless coronary alterations, which are a consequence of atherosclerotic plaque formation and complications with a reduced blood flow supply to the myocardium, are the benchmark of MI. Results: Evidence indicates a close relationship between the MI and some coronary risk factors, associated with this pathologic pattern with a different, but high rate. Conclusion: Precipitating events to cause acute myocardial pathology need, however, to develop an acute myocardial infarction.Keywords: Myocardial infarction, coronary pathology, sympathetic nervous system, catecholamine release, myocardial necrosis, coronary risk factor(s).
Current Pharmaceutical Design
Title:Myocardial Infarction. Pathological Relevance and Relationship with Coronary Risk Factors
Volume: 23 Issue: 22
Author(s): Aurelio Leone*
Affiliation:
- Castelnuovo Magra,Italy
Keywords: Myocardial infarction, coronary pathology, sympathetic nervous system, catecholamine release, myocardial necrosis, coronary risk factor(s).
Abstract: Background: Three types of necrosis characterize MI: coagulation necrosis, typically due to a coronarogenic mechanism, coagulative myocytolysis with formation of contract bands as an effect of sympathetic nervous system and adrenergic stimulation, and colliquative myocytolysis, characterized by myocardial fiber lysis, which is a close result of hydrolytic enzyme activity deriving from the material reaching the infarct area.
Methods: Although a multifactorial etiology may be identified, nevertheless coronary alterations, which are a consequence of atherosclerotic plaque formation and complications with a reduced blood flow supply to the myocardium, are the benchmark of MI. Results: Evidence indicates a close relationship between the MI and some coronary risk factors, associated with this pathologic pattern with a different, but high rate. Conclusion: Precipitating events to cause acute myocardial pathology need, however, to develop an acute myocardial infarction.Export Options
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Cite this article as:
Leone Aurelio *, Myocardial Infarction. Pathological Relevance and Relationship with Coronary Risk Factors, Current Pharmaceutical Design 2017; 23 (22) . https://dx.doi.org/10.2174/1381612823666170317123426
DOI https://dx.doi.org/10.2174/1381612823666170317123426 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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